DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and Serpina1f

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_080963.2	Gene:	Serpina1f / 68348	MGIID:	1915598	Length:	411	Species:	Mus musculus

Alignment Length:	386	Identity:	83/386 - (21%)
Similarity:	176/386 - (45%)	Gaps:	43/386 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VTSVACQTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSAL-----GLPSE 69
            |....|..|..:::.:::...|.|::.||:.:...:||:.:|:.|:.:|.:...|     |||..
Mouse    44 VALTICNVSITLFKKMAQLSGNGNILFSPIRVIAAISMLSLGSNGNLSKHILETLRFNKTGLPEA 108

  Fly    70 DKEAVAARYGALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPV 134
            :   :...:..||:.:...||...|:..:.::::...:....:...|::.:.|:..||:.|:...
Mouse   109 E---IHKCFWYLLHSIHQTEEPSSLQTGSSVFIHQDLTSVDKFVKGVKDLYHSDMISINFTDSSQ 170

  Fly   135 AAERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKS 199
            |..:||.:|::::..:|..::.  ::.||....:||.|.:..:.:|.|.....:...:.:....:
Mouse   171 AKTQINNYVMEKSQKEIVNIVK--NLESDTFLAVVNYIIWNAKLDSNFGCRSVKVKDYHLGYGMT 233

  Fly   200 VPVQMMAQMGTFRANYFRDLDAQVIELPYLNSNLSMTIFLPREVEGLSALEEKIV-----GFARP 259
            :.|.|:..|.........||.:.|:.|..|..|.: |.|:..:...:..:|:.:.     ...|.
Mouse   234 IKVPMIHNMAMHYLFRVEDLSSTVLMLTLLTGNFA-TYFIIPDPGKMQKVEQSLTYPHFRRMRRQ 297

  Fly   260 LVAKEVYLKLPKFKIEFRDELKETLEKLGIRELF---TDKSDLSGLFADKSGGKVSQVSHKAFLE 321
            |:.:.|.|::|:..:....:|:..:..|||..:|   |:.||::....     |..:|..||.|.
Mouse   298 LLTRLVDLEIPELSLSETHDLESMMSLLGITYVFNSGTNSSDMNDTLQ-----KSFKVVSKAVLT 357

  Fly   322 VNEEGAEAA--------GATSVAVTNRAGFSTFLMADHPFAFVIRD-ANTI-YFQGRVVSP 372
            ::|:|::.:        |:|.:.         .:..:.||...|:| .|.: .|.||||:|
Mouse   358 IDEKGSKPSTNSCFKKLGSTDMG---------RMQLNRPFLIFIQDHTNDVPLFLGRVVNP 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	77/375 (21%)
Serpina1f	NP_080963.2	Serpin	48..409	CDD:278507	81/380 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100