DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and Serpina5

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001231668.1	Gene:	Serpina5 / 65051	RGDID:	619817	Length:	442	Species:	Rattus norvegicus

Alignment Length:	377	Identity:	105/377 - (27%)
Similarity:	192/377 - (50%)	Gaps:	20/377 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VTSVACQTSKE----IYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLPSE- 69
            |.:|....|::    :|:.|:.....||:..||:|:...|.|:.:|:...|..::...|||..:
  Rat    72 VGAVGTSRSRDFAFRLYRALASEAPGQNVFFSPMSVSMSLGMLSLGSGLKTKAQILEGLGLSLQQ 136

  Fly    70 -DKEAVAARYGALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGP 133
             .::.:...:..||.......:|..|.|.:.::.:....:..::..|::..:.|:..|.:..|..
  Rat   137 GQEDMLHKGFQQLLQQFSQPSDGLQLSLGSALFTDPAVHIRDHFLSAMKTLYMSDMFSTNFGNPE 201

  Fly   134 VAAERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANK 198
            .|.::||.:|..:|:|||..:|.  .:.|....::||.|:||.:|::.|....|....:.||..|
  Rat   202 SAKKQINDYVAKKTNGKIVDLIK--DLDSTHVMVVVNYIFFKAKWQTAFSSTNTHKMDYHVTPKK 264

  Fly   199 SVPVQMMAQMGTFRANYFRDLDAQVIELPYLNSNLSMTIFLPRE------VEGLSALEEKIVGFA 257
            ::.|.||.:...:.....:::...|:.:||..:..::.| ||.|      .:||.  |..:..:.
  Rat   265 TIQVPMMNREDIYSYILDQNISCTVVGIPYQGNTFALFI-LPSEGKMKRVEDGLD--ERTLRNWL 326

  Fly   258 RPLVAKEVYLKLPKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGKVSQVSHKAFLEV 322
            :....:::.|.||||.||...:|::.|.||||:::||..:||||| .|.:..|:|::.||:.:||
  Rat   327 KMFTKRQLDLYLPKFSIEGTYKLEKILPKLGIQDIFTTHADLSGL-TDHTNIKLSEMVHKSMVEV 390

  Fly   323 NEEGAEAAGATSVAVTNRAGFSTFLMAD--HPFAFVIRDANTIYFQGRVVSP 372
            :|.|..||.:|.:..|.|:...:.|..:  .||..||.|...:||.|:|:.|
  Rat   391 DESGTTAAASTGILFTLRSARPSSLKVEFTRPFLVVIMDGTNLYFIGKVIQP 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	101/366 (28%)
Serpina5	NP_001231668.1	alpha-1-antitrypsin_like	81..439	CDD:239011	100/363 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010