Protein Alignment Spn42Dd and SERPINE3

DIOPT Version :10

• Sequence 1: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001094790.1
• Gene: SERPINE3 / 647174
• HGNCID: 24774
• Length: 424
• Species: Homo sapiens
• Alignment Length: 398
• Identity: 112/398 - (28%)
• Similarity: 181/398 - (45%)
• Gaps: 69/398 - (17%)

  Fly    10 VTSVACQTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLPSED---K 71
            :|.:..:.:..:||.::......|.|:||..:...|.::..||||||.::|..|||....|   |
Human    26 MTLLKTEFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTVHDKRVK 90

  Fly    72 EAVAARYGALLNDLQGQEEGPILKLANRIYVNDQYSLNQNY--------NLAVREPFKSEAESIS 128
            :.:.|.|..|....||.|    ::||..::|.....|:..:        |.::.....||..|.:
Human    91 DFLHAVYATLPTSSQGTE----MELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEPNSTA 151

  Fly   129 L---------TNGPVAAERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDP 184
            :         |.|...:|....|..:|.|.....::            ||:.:.|:|.|..:|..
Human   152 IQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQLV------------LVSTMSFQGTWRKRFSS 204

  Fly   185 AKTRASTFQVTANKSVPVQMMAQMGTFRANY--FRDL---DAQVIELPYLNSNLSMTIFLPREVE 244
            ..|:...|.......:.|.||.|  |...||  |:|.   ...|:|||||.|.:|:.:.|||:.:
Human   205 TDTQILPFTCAYGLVLQVPMMHQ--TTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFLVLPRDKD 267

  Fly   245 -GLSALEEKIVGFARPLVAKEVYL------------KLPKFKIEFRDELKETLEKLGIRELFTD- 295
             .||.:|..       |.|..::|            .||:|:|:.:..||..|...|:.:||..
Human   268 TPLSHIEPH-------LTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLKSILNSWGVTDLFDPL 325

  Fly   296 KSDLSGLFADKSGGKVSQVSHKAFLEVNEEGAEAAGATSVAVTNRAGFSTFLMADHPFAFVIRDA 360
            |::|.|: :.:.|..||:..|||.:||.|||.:|:|||::.:..|:....| .||.||.:.:|:.
Human   326 KANLKGI-SGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRSRIPIF-KADRPFIYFLREP 388

  Fly   361 N---TIYF 365
            |   |::|
Human   389 NTGITVFF 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	serpin42Dd-like_insects	12..372	CDD:381070	111/396 (28%)
SERPINE3	NP_001094790.1	serpinE3	18..400	CDD:381040	112/398 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..174		6/30 (20%)