Protein Alignment Spn42Dd and SERPINB4

DIOPT Version :10

• Sequence 1: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_002965.1
• Gene: SERPINB4 / 6318
• HGNCID: 10570
• Length: 390
• Species: Homo sapiens
• Alignment Length: 381
• Identity: 142/381 - (37%)
• Similarity: 206/381 - (54%)
• Gaps: 32/381 - (8%)

  Fly    20 EIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLP--SEDKEAVAARYGA-- 80
            :::|...||..| |:..||:||.:.|.||.:||:.:||:::...|...  :|:....||.|..
Human    14 DLFQQFRKSKEN-NIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENTTEKAATYHVDR 77

  Fly    81 ----------LLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGP-V 134
                      ||.:.....:...||:||:::....|...|.|..|:::.:::..||....|.| .
Human    78 SGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKFYQTSVESTDFANAPEE 142

  Fly   135 AAERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKS 199
            :.::||.||..||:.|||.:...|::.:|...:||||||||||||:||....|:...|....|..
Human   143 SRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYFKGQWENKFKKENTKEEKFWPNKNTY 207

  Fly   200 VPVQMMAQMGTFRANYFRDLDAQVIELPYLNSNLSMTIFLPREVEGLSALEEKIVGFARPLV--- 261
            ..||||.|..:|......|:.|:|:|:||...:|||.:.||.|::||..||||:.  |..|:
Human   208 KSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLT--AEKLMEWT 270

  Fly   262 ----AKE--VYLKLPKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGKVSQVSHKAFL 320
                .:|  |.|.||:||:|...:||:||..:|:..:|...:||||: ....|..||:|.||||:
Human   271 SLQNMRETCVDLHLPRFKMEESYDLKDTLRTMGMVNIFNGDADLSGM-TWSHGLSVSKVLHKAFV 334

  Fly   321 EVNEEGAEAAGATSVAVTNRAGFST--FLMADHPFAFVIRD--ANTIYFQGRVVSP 372
            ||.|||.|||.||:|.|...:..||  ....:|||.|.||.  .|:|.|.||..||
Human   335 EVTEEGVEAAAATAVVVVELSSPSTNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	serpin42Dd-like_insects	12..372	CDD:381070	140/379 (37%)
SERPINB4	NP_002965.1	serpinB3_B4_SCCA1_2	1..390	CDD:381030	140/379 (37%)