DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn42Dd and serpinb1l2

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001038636.1	Gene:	serpinb1l2 / 568898	ZFINID:	ZDB-GENE-041001-117	Length:	382	Species:	Danio rerio

Alignment Length:	373	Identity:	138/373 - (36%)
Similarity:	205/373 - (54%)	Gaps:	25/373 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 EIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLPSEDKEAVAARYGALLND 84
            ::|:.||.|....|:..||:||...||||::||.|.||.|::..|...|...  ..|.:..|::.
Zfish    14 DLYRALSASSAEGNIFFSPLSISAALSMVYLGARGDTAGEMEKVLCFSSVSD--FHAHFKTLISS 76

  Fly    85 LQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAAER-INQWVLDQTS 148
            :.......||:||||:|....:|....|..:..:.:.:|.:::........:.: ||:||..||.
Zfish    77 INSPSASYILRLANRLYGEKTFSFLPMYVDSTMKLYHAEPQTVDFIRAADDSRQFINKWVEKQTE 141

  Fly   149 GKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGTFRA 213
            .:||.::.||.:....:.||||||||||.|...||...|:...|::..|:|.|||||.|:..|..
Zfish   142 NQIKDLLQPGVVNEMTRLLLVNAIYFKGNWMHTFDAHATKEMPFKINQNESRPVQMMDQVENFPY 206

  Fly   214 NYFRDLDAQVIELPYLNSNLSMTIFLPREV----EGLSALE-----EKIVGF---ARPLVAKEVY 266
            ....:...||:||||....|||.|.||.|:    :.|..||     :|::.:   .:....:::.
Zfish   207 RCIPEYKLQVLELPYTQQELSMLILLPDEIKYGSDPLLKLESELNLQKLLDWTSRGKMDTWRKII 271

  Fly   267 LKLPKFKIEFRDELKETLEKLGIRELFTD-KSDLSGLFADKSGGK-VSQVSHKAFLEVNEEGAEA 329
            ::|||||:|....|.|||||:|:..:|.: |:||:|:  ..:||. :|.|.||||:||||||.||
Zfish   272 VRLPKFKLEIESCLSETLEKMGMSSVFQETKADLTGM--SSNGGLFLSAVIHKAFVEVNEEGTEA 334

  Fly   330 AGATSVAVTNRA---GFSTFLMADHPFAFVIR--DANTIYFQGRVVSP 372
            |.||::.:...|   .|..|: |||||.|.||  ..|:|.|.||..:|
Zfish   335 AAATALLLPISACQGAFHDFI-ADHPFMFFIRHNPTNSILFLGRFRAP 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	136/368 (37%)
serpinb1l2	NP_001038636.1	SERPIN	5..381	CDD:294093	137/371 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	229	1.000	Domainoid score	I2400
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8430
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.830