DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and serpina7

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	XP_021331940.1	Gene:	serpina7 / 564060	ZFINID:	ZDB-GENE-041010-47	Length:	425	Species:	Danio rerio

Alignment Length:	410	Identity:	111/410 - (27%)
Similarity:	202/410 - (49%)	Gaps:	52/410 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IFLWV---TSVACQTSKEIYQ-------------------------LLSKSHTNQNLVVSPVSIE 42
            :|||:   ..|.|...:.:.|                         :.|..:.::|:..||.|:.
Zfish    21 VFLWIFGFAIVVCGNQETLQQPPISAKLPSLINMNNDFAFHLYKRLIESPDYQSKNIFFSPFSVS 85

  Fly    43 TILSMVFMGAEGSTAKELQSALGLPSE--DKEAVAARYGALLNDLQGQEEGPILKLANRIYVNDQ 105
            ..||.:.:||.|.|.::|.|.:|..|.  ..|.:...:.:||.::..:.|..| .:...:|.:|:
Zfish    86 MALSELSLGAGGDTKQQLLSGIGYNSAIFSTEEMHQLFHSLLEEIGNRTEVDI-DVGTALYASDR 149

  Fly   106 YSLNQNYNLAVREPFKSEAESISLTNGPVAAERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVN 170
            :..:..:...::|.:.|:..::.. :.....::||::|.::|.|||...:|  ::..|....|:.
Zfish   150 FKPHSKFLEDMKEFYHSDGFTVDF-SVKETVDQINKYVEEKTHGKISQAVD--NLEKDTLMFLLT 211

  Fly   171 AIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGTFRANYFRDLDAQVIELPYLNSNLSM 235
            .|||||:|:..|.|..|..|||.:....:||||||.|....:..|..:|..:|:.|.| |.:.||
Zfish   212 YIYFKGKWDKPFKPETTSESTFYIDDKTTVPVQMMHQYEHLKVYYDVELFTKVLCLDY-NDSFSM 275

  Fly   236 TIFLP---------REVEGLSALEEKIVGFARPLVAKEVYLKLPKFKIEFRDELKETLEKLGIRE 291
            .:.:|         :::| ::...:.|..:.|.:..::|.:.:||..::....||:.|:.:|:.:
Zfish   276 ILAVPDVYMKQKTMKDLE-MTVSRQHIEKWRRSVSERKVDIYVPKLSLKTSYSLKDILKGMGMTD 339

  Fly   292 LFTDKSDLSGLFADKSGGKVSQVSHKAFLEVNEEGAEAAGATSVAV--TNRAGFSTFLMADHPFA 354
            :|:||:|.:|:  .:....||:|.|||.|:::|:|..||..|.|.:  |:....|. |..||||.
Zfish   340 MFSDKADFTGV--SEENIFVSKVLHKATLDIDEQGTTAAAVTGVEIRPTSYDPLSD-LKFDHPFM 401

  Fly   355 FVIRDA--NTIYFQGRVVSP 372
            ..|.|.  :.|.|.|:||:|
Zfish   402 IFITDQTNDNILFVGKVVNP 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	103/392 (26%)
serpina7	XP_021331940.1	alpha-1-antitrypsin_like	54..418	CDD:239011	102/372 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010