DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and serpini1

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001122164.1	Gene:	serpini1 / 557627	ZFINID:	ZDB-GENE-060503-390	Length:	415	Species:	Danio rerio

Alignment Length:	379	Identity:	133/379 - (35%)
Similarity:	214/379 - (56%)	Gaps:	21/379 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 VACQTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLP--SEDKEAVA 75
            |..:.|..:|..|..|...:|::.||:|:...|.||.:||.||:.:|::.|:|..  .||:|...
Zfish    27 VTAEFSVRLYHQLQISSGEENIIFSPLSVALALGMVELGARGSSLQEIRQAVGYSHFREDEEFSL 91

  Fly    76 ARYGALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAAERIN 140
            .|  .|...|...||..:::|||.:::......|:::...:::.|::|.|::..:.....|||||
Zfish    92 LR--NLSQALSTDEEQYVVRLANSLFLQSGVHFNEDFLQLMKKYFRAEVETVDFSQSTAVAERIN 154

  Fly   141 QWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMM 205
            .|||:.|..||:.::.....:|....:||||:||:|.|:::|.|..||..:|.......|...||
Zfish   155 SWVLNHTESKIQNLVSAEDFSSSTMIMLVNAVYFRGSWKNQFRPENTRTFSFTRDDGSEVQTLMM 219

  Fly   206 AQMGTFRANYFRD--LDA----QVIELPYLNSNLSMTIFLPREVEGLSALEEKIVG-----FARP 259
            .|.|.|....|.|  .:|    ||:|:.|...::||.|.|||:...|::||..|..     :|..
Zfish   220 YQQGDFYYGEFSDGTTEAGGVYQVLEMLYEGEDMSMMIVLPRQEVPLASLEPIIKAPLLEEWANN 284

  Fly   260 LVAKEVYLKLPKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGK---VSQVSHKAFLE 321
            :..::|.:.||:||:|.:.:|:|:|::||||.:|:..:|||.:.|..:.|:   :.:...||:||
Zfish   285 VKRQKVEVYLPRFKVEQKIDLRESLQQLGIRSIFSKDADLSAMTAQMTDGQDLFIGKAVQKAYLE 349

  Fly   322 VNEEGAE-AAGATSVAVTNRAGFSTFLMADHPFAFVIRDANT--IYFQGRVVSP 372
            |.||||| |||:..:|:|........:||||||.|:||:..|  |.|.|||::|
Zfish   350 VTEEGAEGAAGSGMIALTRTLVLYPQVMADHPFFFIIRNRKTGSILFMGRVMNP 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	129/371 (35%)
serpini1	NP_001122164.1	SERPIN	25..414	CDD:294093	133/379 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	217	1.000	Inparanoid score	I3573
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm6540
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.980