DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and serpine3

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001116709.1	Gene:	serpine3 / 556612	ZFINID:	ZDB-GENE-050309-223	Length:	417	Species:	Danio rerio

Alignment Length:	420	Identity:	116/420 - (27%)
Similarity:	197/420 - (46%)	Gaps:	66/420 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LCIFLWVTSVACQTSKEI----------------YQLLSKSHTNQNLVVSPVSIETILSMVFMGA 52
            |.|.||:..: |..:..:                ||.|:::....||:|||.|:...|.::.:||
Zfish     9 LFICLWLVDL-CHVANSVLSSSFSDLHTQFGISLYQTLTETENKSNLIVSPASVSLCLGLLQLGA 72

  Fly    53 EGSTAKELQSALGLPSEDKEAVAARYGALLN----DLQGQEEGPILKLANRIYVNDQYSLNQNYN 113
            .|:|..:|:..||....|     .|...:|:    ||....||..|:|||.:::.....|...:.
Zfish    73 RGNTLVQLEGTLGYDVND-----VRVQNILSRPQGDLANSSEGLRLQLANALFIQTGVKLLPEFT 132

  Fly   114 LAVREPFKSEAESISLTNGPVAAERINQWV---------------LDQTSGKIKGMIDPGSMTSD 163
            ........:...|::.:|......|:.||.               |..:||:     :..:...|
Zfish   133 QHALGWGNTSLLSVNFSNPNHTHSRLQQWAHYQSKADDHLQTREELHHSSGE-----EEEATRQD 192

  Fly   164 --VKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGTFRANYFR---DLDAQV 223
              :...||:.:.|.|.|:.:|...:|:...|..:...:|.|.||.|.......:||   :.:..|
Zfish   193 HLLYMALVSTLVFHGAWQKQFLFTETQNLPFTFSDGSTVKVPMMYQSSEVNIGHFRLPSEQEYTV 257

  Fly   224 IELPYLNSNLSMTIFLPREVE-GLSALEEKIVGFARPLVAKEVYLK-------LPKFKIEFRDEL 280
            :|||||:.:|.:.:.||.:.: .||.||::|.  ||.:...:..|:       ||:||::.:..|
Zfish   258 LELPYLDHSLRLLVALPSDRKTPLSQLEKQIT--ARAVGLWDTGLRRTKMDIFLPRFKMQSKINL 320

  Fly   281 KETLEKLGIRELFT-DKSDLSGLFADKSGGKVSQVSHKAFLEVNEEGAEAAGATSVAVTNRAGFS 344
            |..|:.||:.::|: ..:|..|: :|..|..||:..|:|.:||.|.|.:||.||::.:..|:..:
Zfish   321 KPVLQSLGVSDIFSPSAADFRGI-SDTDGIFVSEAFHEARIEVTEAGTKAASATAMVLLKRSRSA 384

  Fly   345 TFLMADHPFAFVIRDANT--IYFQGRVVSP 372
            .| .||.||.|::|..:|  :.|.||||:|
Zfish   385 VF-KADRPFLFILRQISTGSLLFIGRVVNP 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	107/403 (27%)
serpine3	NP_001116709.1	Serpin	35..413	CDD:278507	110/391 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020