Protein Alignment Spn42Dd and SERPINB8

DIOPT Version :9

• Sequence 1: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001353127.1
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Alignment Length: 364
• Identity: 127/364 - (34%)
• Similarity: 202/364 - (55%)
• Gaps: 16/364 - (4%)

  Fly    21 IYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLPSEDKEAVAARYGALLNDL 85
            ::::|.:...::|:..||:||.:.|:||||||:||||.::..||.|..:..  :...:.:||:::
Human    15 LFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGD--IHRGFQSLLSEV 77

  Fly    86 QGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAAER-INQWVLDQTSG 149
            .......:|:.|||::.........::....::.:::|.|.:|.........: ||.||.::|.|
Human    78 NRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEG 142

  Fly   150 KIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGTFRAN 214
            ||..::|.|::....|.:|||||||||:|..:||...||...|:....|.. ||||.:...|:..
Human   143 KISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKT-VQMMFKEAKFKMG 206

  Fly   215 YFRDLDAQVIELPYLNSNLSMTIFLPREVEGLSALE-----EKIVGF--ARPLVAKEVYLKLPKF 272
            |..::..||:||||:...|||.|.||.:...|:.:|     ||...:  :..|...:|.:.||:.
Human   207 YADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRL 271

  Fly   273 KIEFRDELKETLEKLGIRELFTD-KSDLSGLFADKSGGKVSQVSHKAFLEVNEEGAEAAGATSVA 336
            |:|...:|:..|.:||:.:.|.: |:|.||:..:|: ..:|:|:||.|:||||||.|||.||:|.
Human   272 KLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKN-VPLSKVAHKCFVEVNEEGTEAAAATAVV 335

  Fly   337 VTNRAG-FSTFLMADHPFAFVIR--DANTIYFQGRVVSP 372
            ..:|.. ......|||||.|.||  ..|.|.|.||..||
Human   336 RNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	124/359 (35%)
SERPINB8	NP_001353127.1	SERPIN	4..374	CDD:320777	125/362 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.930