Protein Alignment Spn42Dd and SERPINE2

DIOPT Version :9

• Sequence 1: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: XP_005246698.1
• Gene: SERPINE2 / 5270
• HGNCID: 8951
• Length: 410
• Species: Homo sapiens
• Alignment Length: 390
• Identity: 117/390 - (30%)
• Similarity: 196/390 - (50%)
• Gaps: 41/390 - (10%)

  Fly     8 LWVTSVACQTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLPSEDKE 72
            |.:..:...|..:::..:.||..:.|:|:||..|.::|.|:.:||:|.|.|:|
Human    37 LSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQL------------ 89

  Fly    73 AVAARYGA-----LLNDLQ----GQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESIS 128
            |:..|||.     :|..:.    .::...|:.:||.::|.:...:...:....::.|:.|..:::
Human    90 AMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVN 154

  Fly   129 LTNGPVAAERINQWVLDQTSGKIKGMIDP----GSMTSDVKALLVNAIYFKGQWESKFDPAKTRA 189
            ..:...|.:.||.||.::|...|..::.|    |.:|   :.:||||:||||.|:|:|.|..|:.
Human   155 FEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLT---RLVLVNAVYFKGLWKSRFQPENTKK 216

  Fly   190 STFQVTANKSVPVQMMAQMGTFRANYF---RDLDAQVIELPYLNSNLSMTIFLPREVE-GLSAL- 249
            .||.....||..|.|:||:..||....   .||....|||||...::||.|.||.|.. .|||:
Human   217 RTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAII 281

  Fly   250 ----EEKIVGFARPLVAKEVYLKLPKFKIEFRDELKETLEKLGIRELF-TDKSDLSGLFADKSGG 309
                .:.|..:...:|.|.|.:.||||....:.:|||.|:.|||.::| :.|::.:.:.......
Human   282 PHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENL 346

  Fly   310 KVSQVSHKAFLEVNEEGAEAAGATSVAVTNRAGFSTFLMADHPFAFVIRDANT--IYFQGRVVSP 372
            .||.:..||.:||:|:|.:|:.||:..:..|:....|:: |.||.|.||...|  :.|.|::..|
Human   347 HVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIV-DRPFLFFIRHNPTGAVLFMGQINKP 410

  Fly   373  372
            Human   411  410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	115/377 (31%)
SERPINE2	XP_005246698.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9820
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.030