Protein Alignment Spn42Dd and SERPINA5

DIOPT Version :10

• Sequence 1: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_000615.3
• Gene: SERPINA5 / 5104
• HGNCID: 8723
• Length: 406
• Species: Homo sapiens
• Alignment Length: 364
• Identity: 116/364 - (31%)
• Similarity: 193/364 - (53%)
• Gaps: 19/364 - (5%)

  Fly    20 EIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGL---PSEDKEAVAARYGAL 81
            ::|:.|:.:..:|::..|||||...|:|:.:||..||..::...|||   .|.:|| :...:..|
Human    51 DLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKE-LHRGFQQL 114

  Fly    82 LNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAAERINQWVLDQ 146
            |.:|....:|..|.|.|.::.:....|...:..|::..:.::....:..:...|.::||.:|..|
Human   115 LQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAKQ 179

  Fly   147 TSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGTF 211
            |.|||..::.  ::.|:...::||.|:||.:||:.|:...|:...|.||:...|.|.||::...:
Human   180 TKGKIVDLLK--NLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSREDQY 242

  Fly   212 RANYFRDLDAQVIELPYLNSNLSMTIFLPRE-----VE-GLSALEEKIVGFARPLVAKEVYLKLP 270
            .....|:|..:|:.:|| ..|.:....||.|     || |||  |:.:..:.:....:::.|.||
Human   243 HYLLDRNLSCRVVGVPY-QGNATALFILPSEGKMQQVENGLS--EKTLRKWLKMFKKRQLELYLP 304

  Fly   271 KFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGKVSQVSHKAFLEVNEEGAEAAGATSV 335
            ||.||...:|::.|..|||..:||..:||||: ::.|..:||::.|||.:||:|.|..||.||..
Human   305 KFSIEGSYQLEKVLPSLGISNVFTSHADLSGI-SNHSNIQVSEMVHKAVVEVDESGTRAAAATGT 368

  Fly   336 AVTNRAG--FSTFLMADHPFAFVIRDANTIYFQGRVVSP 372
            ..|.|:.  .|..|:.:.||...|.| |.|.|.|:|..|
Human   369 IFTFRSARLNSQRLVFNRPFLMFIVD-NNILFLGKVNRP 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	serpin42Dd-like_insects	12..372	CDD:381070	115/362 (32%)
SERPINA5	NP_000615.3	serpinA5_PCI	44..406	CDD:381021	115/362 (32%)