DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and serpinb1l1

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001009892.2	Gene:	serpinb1l1 / 494155	ZFINID:	ZDB-GENE-040715-5	Length:	384	Species:	Danio rerio

Alignment Length:	377	Identity:	136/377 - (36%)
Similarity:	208/377 - (55%)	Gaps:	22/377 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 QTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLPS---EDKEAVAAR 77
            |.|..:::.:|..:.:.|:..|||||.:.|:||.:||:|:||.::...||..|   :..|.:.:.
Zfish    10 QFSLNLFKKISGGNASGNVFYSPVSISSALAMVSLGAKGNTADQMFKVLGFNSQAHQPVEQIHSN 74

  Fly    78 YGALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTN-GPVAAERINQ 141
            :...:::|...|...:|.||||:|....|.|.:.:....:..:.:..|.:...| ...|...||.
Zfish    75 FKKFMSELNKPEAPYVLSLANRLYGEQTYQLIEKFLNDTKRYYDAGLEKVDFINKSEDARVNINT 139

  Fly   142 WVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMA 206
            ||...|..|||.::..|::.:..:.:|||||||||.||.||....||...|::..|::.||:||.
Zfish   140 WVEKNTQEKIKDLLPSGAIDAMTRLVLVNAIYFKGNWEEKFPKEATRDGVFRLNKNQTKPVKMMH 204

  Fly   207 QMGTFRANYFRDLDAQVIELPYLNSNLSMTIFLPREVE----GLSALE-----EKIVGFARPLV- 261
            |...|.:.|..::.:.|:||||...||||.|.||.|:|    ||..||     ||::.:.:|.|
Zfish   205 QKAEFPSGYIEEMKSHVLELPYAGKNLSMLIILPDEIEDETTGLQKLERALTYEKLMEWTKPEVM 269

  Fly   262 -AKEVYLKLPKFKIEFRDELKETLEKLGIRELF-TDKSDLSGLFADKSGGKVSQVSHKAFLEVNE 324
             .:||.:.|||||.|...::|..|..:|:.::| ..|.:|:|: :..:...:|:..||||:||||
Zfish   270 HQREVQVSLPKFKTEQTYDMKSLLVSMGMEDVFDPQKVNLTGM-SSSNDLVLSKAIHKAFVEVNE 333

  Fly   325 EGAEAAGATSVAVTNRAGFSTFLM--ADHPFAFVIR--DANTIYFQGRVVSP 372
            ||.|||.||: |:.....:...|.  |||||.|.||  ...:|.|.||:.||
Zfish   334 EGTEAAAATA-AIEKLMCYIPPLSFNADHPFLFFIRHNPTKSILFYGRLCSP 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	133/372 (36%)
serpinb1l1	NP_001009892.2	PAI-2	4..384	CDD:239013	134/375 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8430
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.730