DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and serpinc1

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001008153.1	Gene:	serpinc1 / 493515	XenbaseID:	XB-GENE-975782	Length:	456	Species:	Xenopus tropicalis

Alignment Length:	372	Identity:	122/372 - (32%)
Similarity:	190/372 - (51%)	Gaps:	25/372 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 YQLLSKSHTN-QNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLP--SEDKEAVAARYGALLN 83
            |:.|:.|..| :|:.:||:||....:|..:||..:|.|||.......  ||........:.|.||
Frog    86 YKNLADSKQNTENIFMSPLSISQAFTMAKLGACNNTLKELMEVFYFDTISERASDQIHYFFAKLN 150

  Fly    84 D--LQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGP-VAAERINQWVLD 145
            .  .:...:...|...||::.....:.|:.|.......:.::...::....| ::.|.||.||.|
Frog   151 CRLFRKANKSSELVSVNRLFGEKSLTFNETYQDISELVYGAKLLPLNFKEKPELSREIINNWVSD 215

  Fly   146 QTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGT 210
            :|..:|..:|..|.:|.|...:|:|||||||.|:|||:...|:...|....:.......|.|.|.
Frog   216 KTEKRITDVIPVGVITPDTVLVLINAIYFKGLWKSKFNSENTKMEQFYPDESNHCLAATMYQEGI 280

  Fly   211 FRANYFRDLDAQVIELPYLNSNLSMTIFLPREVEGLSALE-----EKIVGFARPLVAKEVYLKLP 270
            ||.:.|:|...||:||||...:::|.:.||.....|..:|     ||:..:.:.....::.:.||
Frog   281 FRYSSFKDDGVQVLELPYKGDDITMVLVLPSPETPLMKVEQNLTLEKLGNWLQKSRELQLSVYLP 345

  Fly   271 KFKIEFRDELKETLEKLGIRELFTDKS-DLSGLFADKSGGK----VSQVSHKAFLEVNEEGAEAA 330
            :|::|....:||.|:::|:.:||...| .|.|:.|   ||:    ||...|||||||||||:|||
Frog   346 RFRVEDSFSVKEKLQQMGLVDLFDPNSAKLPGIVA---GGRTDLYVSDAFHKAFLEVNEEGSEAA 407

  Fly   331 GATSVAVTNRA---GFSTFLMADHPFAFVIRDA--NTIYFQGRVVSP 372
            .:|:|.:|.|:   ...|| .|:.||...||:.  |::.|.|||.:|
Frog   408 ASTAVILTGRSLNLNRITF-RANRPFLVFIREVAINSVLFMGRVANP 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	119/367 (32%)
serpinc1	NP_001008153.1	serpinC1_AT3	61..455	CDD:381002	122/372 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.110