Protein Alignment Spn42Dd and SERPINC1

DIOPT Version :9

• Sequence 1: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Alignment Length: 444
• Identity: 134/444 - (30%)
• Similarity: 202/444 - (45%)
• Gaps: 100/444 - (22%)

  Fly     8 LWVTSVA-CQTSKEIYQLLSKS-HTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLP--S 68
            :|..|.| .:.:...||.|:.| :.|.|:.:||:||.|..:|..:||...|.::|.......  |
Human    80 VWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTIS 144

  Fly    69 EDKEAVAARYGALLNDLQGQEEGPILKL--ANRIYVNDQYSLNQNYN-------LAVREP--FKS 122
            |........:.|.||....::.....||  |||::.:...:.|:.|.       .|..:|  ||.
Human   145 EKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKE 209

  Fly   123 EAESISLTNGPVAAERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFK------------ 175
            .||.        :...||:||.::|.|:|..:|...::......:|||.||||
Human   210 NAEQ--------SRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKVLRMALERPQGL 266

  Fly   176 -----------------------------GQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGTF 211
                                         |.|:|||.|..||...|.....:|....||.|.|.|
Human   267 PLALQLTPFFFKWRDRSPERANGLPKATQGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKF 331

  Fly   212 RANYFRDLD-AQVIELPYLNSNLSMTIFLPREVEGLSALEEKIVGFARPLVAKE---------VY 266
            |  |.|..: .||:|||:...:::|.:.||:..:.|:.:|:::.    |.|.:|         :.
Human   332 R--YRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELT----PEVLQEWLDELEEMMLV 390

  Fly   267 LKLPKFKIEFRDELKETLEKLGIRELFT-DKSDLSGLFADKSGGK----VSQVSHKAFLEVNEEG 326
            :.:|:|:||....|||.|:.:|:.:||: :||.|.|:.|:   |:    ||...|||||||||||
Human   391 VHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAE---GRDDLYVSDAFHKAFLEVNEEG 452

  Fly   327 AEAAGATSVAVT------NRAGFSTFLMADHPFAFVIRDA--NTIYFQGRVVSP 372
            :|||.:|:|.:.      ||..|.    |:.||...||:.  |||.|.|||.:|
Human   453 SEAAASTAVVIAGRSLNPNRVTFK----ANRPFLVFIREVPLNTIIFMGRVANP 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	128/430 (30%)
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	134/444 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	221	1.000	Domainoid score	I2614
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3541
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.940