DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and Serpina11

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_955018.2	Gene:	Serpina11 / 380780	MGIID:	2685741	Length:	427	Species:	Mus musculus

Alignment Length:	377	Identity:	102/377 - (27%)
Similarity:	186/377 - (49%)	Gaps:	21/377 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VTSVACQTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLPSEDKEAV 74
            ||......:..:|:.|::.... |::.||||:.:.|:::.:||...|..::..:||....:..|.
Mouse    55 VTPTITNFALRLYKQLAEEVAG-NILFSPVSLSSSLALLSLGAHADTQTQILESLGFNLTETPAA 118

  Fly    75 AARYG--ALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAAE 137
            ....|  :||:.|........|||.:.::::.|....|.:..:.:|.:.:.|.|.:.|......:
Mouse   119 DVHRGFQSLLHTLDLPSPKLELKLGHFLFLDRQLKPQQRFLDSAKELYGALAFSANFTEAAATGQ 183

  Fly   138 RINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTR-ASTFQVTANKSVP 201
            :||..|..||.|::.|.:.  ..:.|...:|:|.|:||.:.:..||..:|| ..:|.:.....:.
Mouse   184 QINDLVRKQTYGQVVGCLP--EFSHDTLMVLLNYIFFKAKCKHPFDRYQTRKQESFSLDQRTPLR 246

  Fly   202 VQMMAQMGTFRANYFRDLDAQVIELPYLNSNLSMTIFLP-----REVEGLSALE-EKIVGFARPL 260
            :.||.|....|..|.::....|:::.|..:.| :.:.||     ::||  :||: |.:..:.:..
Mouse   247 IPMMRQKEMHRFLYDQEASCTVLQIEYSGTAL-LLLVLPDPGKMQQVE--AALQPETLRRWGQRF 308

  Fly   261 VAKEVYLKLPKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGKVSQVSHKAFLEVNEE 325
            :...:.|.||:|.|.....|:|.|..:|:..||..::||||:.. :....||:|||||.:::||:
Mouse   309 LPSLLDLHLPRFSISATYNLEEILPLIGLGNLFDMEADLSGIMG-QLNKTVSRVSHKAIVDMNEK 372

  Fly   326 GAEAAGATSVAVTNRAGFSTFLMADH---PFAFVIRDANT--IYFQGRVVSP 372
            |.|||.|:.:.....|...|.....|   ||..::.:..|  :.|.|:||:|
Mouse   373 GTEAAAASGLLSQPPALNMTSAPQAHYNRPFLLLLWEVTTQSLLFLGKVVNP 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	97/366 (27%)
Serpina11	NP_955018.2	SERPIN	58..421	CDD:294093	97/369 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100