DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and Serpina11

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001008776.1	Gene:	Serpina11 / 362774	RGDID:	1359239	Length:	462	Species:	Rattus norvegicus

Alignment Length:	418	Identity:	105/418 - (25%)
Similarity:	191/418 - (45%)	Gaps:	63/418 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VTSVACQTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLPSEDKEAV 74
            ||......:..:|:.|::.... |::.||||:.:.::::.:||...|..::..:||....:..|.
  Rat    50 VTPTITNFALRLYKQLAEEIPG-NILFSPVSLSSTVALLSLGAHADTQAQILQSLGFNLTETPAA 113

  Fly    75 AARYG--ALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAAE 137
            ....|  :||:.|........|||.:.::::.|....|.:..:.:|.:.:.|.|.:.|......:
  Rat   114 DIHRGFQSLLHTLDLPSPKLELKLGHSLFLDRQLKPQQRFLDSAKELYGALAFSANFTEAAATGQ 178

  Fly   138 RINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTR-ASTFQVTANKSVP 201
            :||..|..||.|::.|.:.  ....|...:|:|.|:||.:|:..||..:|| ..:|.|.....:.
  Rat   179 QINDLVRKQTYGQVVGCLP--EFDRDTLMVLLNYIFFKAKWKHPFDRYQTRKQESFFVDQRLQLR 241

  Fly   202 VQMMAQMGTFRANYFRDLDAQVIELPYLNSNLSMTI-------------------------FLPR 241
            :.||.|....|..|.::....|:::.|..:.|.:.:                         ||||
  Rat   242 IPMMRQKEMHRFLYDQEASCTVLQIEYSGTALLLLVLPDPGKMQQVEAALQPETLRRWGQRFLPR 306

  Fly   242 EVE----GLSALE-EKIVGFARPLVAK-------------EVYLKLPKFKIEFRDELKETLEKLG 288
            :.:    |...|. :::..|.:..|.|             .:.|.||:|.:.....|:|.|..:|
  Rat   307 KAQAGGAGNGGLHWDRVNEFPQNRVGKLSLKHLQMTQTWSLLDLHLPRFSVSATYNLEEILPLVG 371

  Fly   289 IRELFTDKSDLSGLFADKSGGKVSQVSHKAFLEVNEEGAEAAGAT-------SVAVTNRAGFSTF 346
            :..||..::||||:.. :....||:|||||.:::||:|.|||.|:       |:.:|: |..:.|
  Rat   372 LSSLFDVEADLSGIMG-QLNKTVSRVSHKAVVDMNEKGTEAAAASGLLSQPPSLNMTS-APHAHF 434

  Fly   347 LMADHPFAFVIRDANT--IYFQGRVVSP 372
               :.||..::.:..|  :.|.|:||:|
  Rat   435 ---NRPFLLLLWEVTTQSLLFLGKVVNP 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	100/407 (25%)
Serpina11	NP_001008776.1	alpha-1-antitrypsin_like	53..456	CDD:239011	100/410 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010