DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and Spn42Db

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_610244.2	Gene:	Spn42Db / 35599	FlyBaseID:	FBgn0033112	Length:	388	Species:	Drosophila melanogaster

Alignment Length:	365	Identity:	116/365 - (31%)
Similarity:	194/365 - (53%)	Gaps:	20/365 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 IYQLLSKSHTNQNLVVSPVSIETILSMVFMG-AEGS-TAKELQSALGLPSEDKEAVAARYGALLN 83
            ::..|.::....|::.||:||....:|:.|| :||| ||||:...|.....:.:.||..:|.:
  Fly    17 LHDHLCRASAGLNIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLRFGGLEAQQVAESFGVV-- 79

  Fly    84 DLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAAERINQWVLDQTS 148
             |:..|:..:||:||.:||.....:::.:...:.:.|:|:...|.. ....||..||:||..||:
  Fly    80 -LKSYEQCQVLKMANGLYVMKGLQVDEQFGHILEQKFRSKPMEIDF-GSEQAASIINKWVESQTN 142

  Fly   149 GKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGTFRA 213
            ..||.:|.|..:|.|.:..|||.|:|||:|...|:..:||...| ..:::...|:||.....|..
  Fly   143 NLIKDIIGPRVLTKDSRLCLVNGIHFKGEWSISFNEKETREEDF-FGSDRPTRVRMMHVCENFFF 206

  Fly   214 NYFRDLDAQVIELPYLNSNLSMTIFLPREVEGLSALEEKIVGFARPLVA-----KEVYLKLPKFK 273
            ......:|..:.:.|...||:|.|.||.|...|::||:|:...:..:|:     ::|.:|:|.|.
  Fly   207 AVLPMFEATALRMNYSACNLAMIILLPDEKSNLTSLEKKLSDISLEVVSSAMNLEKVDVKIPSFT 271

  Fly   274 IEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGKVSQVSHKAFLEVNEEGAEAAGATSVAVT 338
            .||:.||.:.|..:|:..:|:.:::|.|:...:....|||:.||||:|:||.|.|||.||:...|
  Fly   272 AEFQQELSQVLMLMGMNRIFSGQAELGGMLQSEESLFVSQIVHKAFIEINEVGTEAAAATAAVAT 336

  Fly   339 NRA-----GFSTFLMADHPFAFVIRDANT--IYFQGRVVS 371
            .|:     |......|:.||.:.|:| ||  :.|.|..::
  Fly   337 FRSMPARQGPPKVFHANRPFFYAIKD-NTHGLLFAGHFIT 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	116/361 (32%)
Spn42Db	NP_610244.2	SERPIN	12..373	CDD:238101	116/361 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446388
Domainoid	1	1.000	172	1.000	Domainoid score	I1138
eggNOG	1	0.900	-	-		E33208_3BBFJ
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I1521
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D140751at6656
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm1112
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
	10	9.900