DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and Serpina7

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_808588.3	Gene:	Serpina7 / 331535	MGIID:	3041197	Length:	426	Species:	Mus musculus

Alignment Length:	378	Identity:	107/378 - (28%)
Similarity:	185/378 - (48%)	Gaps:	26/378 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SVACQTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLPSEDKEAVAA 76
            |:....:..:|:.||..:.:.|:..|||||...|:|:..|:..||..::...||....|......
Mouse    55 SINADFAFSLYRRLSVENPDLNIFFSPVSISVALAMLSFGSGSSTQTQILEVLGFNLTDTPVTEL 119

  Fly    77 RYG-----ALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAA 136
            :.|     ..||..:.:.|   |::.|.:::..|......:...|:..:::|..|...:|...|.
Mouse   120 QQGFQHLICSLNFPKNELE---LQMGNAVFIGQQLKPLAKFLDDVKTLYETEVFSTDFSNVSAAQ 181

  Fly   137 ERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKT-RASTFQVTANKSV 200
            .:||.:|..||.|||.|:|.  .:..::..:|||.|:|:.||.:.|..:|| .:|.|.|..:.:|
Mouse   182 HKINSYVEKQTKGKIVGLIQ--GLKLNIIMILVNYIHFRAQWANPFRVSKTEESSNFSVDKSTTV 244

  Fly   201 PVQMMAQMGTFRANYFRDLDAQVIELPYLNSNLSMTIFLPRE-----VEGLSALEEKIVGFARPL 260
            .|.||.|:..:......:|:..|:::.|..:.|::.: ||:|     ||  :|:..|.:.....|
Mouse   245 QVPMMHQLEQYYHYVDMELNCTVLQMDYSENALALFV-LPKEGHMEWVE--AAMSSKTLKKWNYL 306

  Fly   261 VAKE-VYLKLPKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGKVSQVSHKAFLEVNE 324
            :.|. |.|.:|||.|....:|..||:|:|:|:.|.:.:|..|:..| ||.|:|...|||.|.:.|
Mouse   307 LQKGWVELFVPKFSISATYDLGSTLQKMGMRDAFAESADFPGITED-SGLKLSYAFHKAVLHIGE 370

  Fly   325 EGAEAAGATSVAVTNR---AGFSTFLMADHPFAFVIRDANT--IYFQGRVVSP 372
            ||.:...:..|...::   ......:..|..|..:|.:..|  :.|.|::|:|
Mouse   371 EGTKEGASPEVGSLDQQEVPPLHPVIRLDRAFLLMILEKRTRSVLFLGKLVNP 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	104/369 (28%)
Serpina7	NP_808588.3	alpha-1-antitrypsin_like	57..419	CDD:239011	103/370 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010