DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and serpina1

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	XP_017207927.1	Gene:	serpina1 / 322701	ZFINID:	ZDB-GENE-030131-1421	Length:	433	Species:	Danio rerio

Alignment Length:	363	Identity:	109/363 - (30%)
Similarity:	188/363 - (51%)	Gaps:	19/363 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 IYQLLSKSHTNQ--NLVVSPVSIETILSMVFMGAEGSTAKELQSALGLPSEDKEAVAARYGALLN 83
            :|:.|:.:...|  |:..|||.|...||::.:||:.||..::.|.||..:...|.|...|..||:
Zfish    77 LYKKLASNPDGQGKNIFFSPVGISMALSLLAVGAKASTLSQIYSGLGYSALTPEQVNEGYEHLLH 141

  Fly    84 DLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAAERINQWVLDQTS 148
            .|...::...|:....:.:.|.:.:...:....:..:.|||..:..:...:||..||:::..:|.
Zfish   142 MLGHSQDAMQLEAGAGVAIRDGFKVVDQFLKDAQHYYNSEAFGVDFSKPEIAAAEINKFIARKTH 206

  Fly   149 GKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGTFRA 213
            .||..|:.  .:.:|...:|:|.:||:|:||..||...|..:.|:|..:.:|.|.||.:.|  |.
Zfish   207 DKITNMVK--DLDADTVMMLINYMYFRGKWEKPFDAKLTHKADFKVDQDTTVQVDMMKRTG--RY 267

  Fly   214 NYFRDLDAQ--VIELPYLNSNLSMTIFLPREVEGLSALEEKIV-----GFARPLVAKEVYLKLPK 271
            :.::|...|  |:.:|| ..|.||.|.||.:.: :..|||.|.     .:...|....|.|.:||
Zfish   268 DIYQDPVNQTTVMMVPY-KGNTSMMIVLPDDGK-MKELEESICRHHLKNWHDKLFRSSVDLFMPK 330

  Fly   272 FKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGKVSQVSHKAFLEVNEEGAEAAGATSVA 336
            |.|....:|...|:.:|:.:.|.||:|.||: .::...|||||.|:|.:.|:|:|.|||..|::.
Zfish   331 FSISATSKLDGILKDMGMTDAFNDKADFSGM-TEEVKVKVSQVLHQAVMSVDEKGTEAAAITTIE 394

  Fly   337 VTNRAGFSTFLMADHPFAFVIRDANT--IYFQGRVVSP 372
            :...:...|.:: :.||..:|.:.:|  |.|.|::.:|
Zfish   395 IMPMSLPDTVIL-NRPFLVLIVEDSTMSILFMGKITNP 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	108/358 (30%)
serpina1	XP_017207927.1	alpha-1-antitrypsin_like	69..428	CDD:239011	108/358 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010