DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and Serpinb1b

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	XP_038952280.1	Gene:	Serpinb1b / 306891	RGDID:	1560658	Length:	380	Species:	Rattus norvegicus

Alignment Length:	370	Identity:	133/370 - (35%)
Similarity:	204/370 - (55%)	Gaps:	20/370 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 EIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTA-KELQSALGLPSEDKEAVAARYGALLN 83
            |::..||:|....| :.||.||.:.|:|||:||:||:| ..|:.|.....:..|.:.:|:.:|..
  Rat    14 ELFHTLSESSPTGN-IFSPFSISSALAMVFLGAKGSSAPSSLRLAETFHFDSVEDIHSRFQSLNA 77

  Fly    84 DLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPV-AAERINQWVLDQT 147
            :::.......||:|||:|....|:....:..:.::.:.::...:...:... |.:.||:||..||
  Rat    78 EMRKHGASHTLKVANRLYGEKTYNFLPEFLASTQKMYGADLAPVDFQHASEDARKEINKWVKGQT 142

  Fly   148 SGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGTFR 212
            .|||..::..|.:.|..|.:|||||||||.|:.||....|..:.|::....:..|:||.|...|.
  Rat   143 EGKIPELLAGGVVNSTTKLVLVNAIYFKGIWQEKFLTRHTTDAPFRLNKKDTKMVKMMYQKEKFP 207

  Fly   213 ANYFRDLDAQVIELPYLNSNLSMTIFLPREVE----GLSALE-----EKIVGFARPLVAKE--VY 266
            ..|..||..:|:|:||....|||.|.||.::|    ||..:|     ||:..:.:....||  |:
  Rat   208 FGYIPDLKCKVLEMPYQGGELSMVILLPEDIEDESTGLQKIEEQLTLEKLYEWTKHENLKEIDVH 272

  Fly   267 LKLPKFKIEFRDELKETLEKLGIRELF-TDKSDLSGLFADKSGGKVSQVSHKAFLEVNEEGAEAA 330
            :.|||||||....|...|.:||:::|| :.|:||||: ::.....:|::.||:|:||||||.|||
  Rat   273 VNLPKFKIEESYILNSNLGRLGLQDLFSSSKADLSGM-SESRDIFISKIVHKSFVEVNEEGTEAA 336

  Fly   331 GATSVAVTNRAGFSTFLMADHPFAFVIR---DANTIYFQGRVVSP 372
            .||:..|..........:.||||.|.||   .||.::| |||.||
  Rat   337 AATAGLVEYCLVSIEAFIVDHPFLFFIRHNPTANMLFF-GRVCSP 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	129/365 (35%)
Serpinb1b	XP_038952280.1	serpinB1_LEI	1..380	CDD:381028	131/368 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm12319
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.930