DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn42Dd and Serpinb13

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001100638.1	Gene:	Serpinb13 / 304690	RGDID:	1304661	Length:	389	Species:	Rattus norvegicus

Alignment Length:	384	Identity:	127/384 - (33%)
Similarity:	204/384 - (53%)	Gaps:	39/384 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 EIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSAL---------GLPSEDK---- 71
            ::::.|:|: ::.|:..||:.|.|.:.|:.:|.:|:||.|||..|         .|.||:|
  Rat    14 DLFKELNKT-SDGNVFFSPLGISTAIGMILLGTQGATASELQKVLYSEQGTGSSRLKSEEKEIEK 77

  Fly    72 -EAVAARYGALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTN-GPV 134
             |.:..::..||.::....:...|.::||:|....|...|.|...|.:.:.:..|.:...| ...
  Rat    78 TEEIHHQFQKLLTEISKPTKDYDLIISNRLYGERTYLFLQKYIDYVEKYYHASLEPVDFVNAADE 142

  Fly   135 AAERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKS 199
            :.::||.||..||:.|:|.:...||:.|..|.:|:|.:||||.|:.:|....|:...|.:..|.|
  Rat   143 SRKKINSWVESQTNEKVKDLFPEGSLNSSTKLVLINTVYFKGLWDREFKKEHTKEEDFWLNKNIS 207

  Fly   200 VPVQMMAQMGTFRANYFRDLDAQVIELPYLNSNLSMTIFLPREVEGLSAL-----EEKIVGFARP 259
            .|||||||..:|......||.|:::.:||.||:.||.:.||.:::||..:     .||:|.:..|
  Rat   208 KPVQMMAQCSSFSFTLLEDLQAKIVGIPYKNSDFSMFVLLPNDIDGLEKIIDKLSPEKLVEWTSP 272

  Fly   260 --LVAKEVYLKLPKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGKVSQVSHKAFLEV 322
              |..::|.|:||:.|:|...:|:.|||.:||...|::.:|.||:.| .||.:.....|::||.|
  Rat   273 GQLKQRKVDLRLPRLKVEETYDLQPTLEAVGIHSAFSEHADYSGMSA-HSGLQTQNFLHRSFLVV 336

  Fly   323 NEEGAEAAGATSVAVTNRAGFSTFLMA-------DHPFAFVI--RDANTIYFQGRVVSP 372
            .|||.||...|.|      ||.....|       :|||.|.:  |::::|.|.||..||
  Rat   337 TEEGVEATAGTGV------GFKVLSAASCELVHCNHPFLFFVRHRESDSILFFGRFSSP 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	124/379 (33%)
Serpinb13	NP_001100638.1	SERPIN	4..389	CDD:294093	125/382 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm12319
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.830