DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and Serpinb11

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	XP_006249694.2	Gene:	Serpinb11 / 304689	RGDID:	1306497	Length:	522	Species:	Rattus norvegicus

Alignment Length:	392	Identity:	121/392 - (30%)
Similarity:	208/392 - (53%)	Gaps:	36/392 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VTSVACQTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALG-------LP 67
            :|:...:...::::.||.|:..:|:..||::....|||:.:||.|.:|::::..|.       |.
  Rat   138 ITTANTEFCLDVFKELSSSNVGENIFFSPLTTFYALSMLLLGARGKSAEQMEKVLHYDNFSGFLK 202

  Fly    68 SEDKEAVAARYG--------ALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEA 124
            ::.|.:.....|        ||::.:..|..   |.:|||||.......::.|.....:.::::.
  Rat   203 AKIKNSSECSQGGRMHPEFRALVSHINQQNS---LSIANRIYGTKAIEFHKQYIRCCEKLYQAKL 264

  Fly   125 ESISLTNGPVAAER----INQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPA 185
            :::..   .::||.    ||.||.::|.|||..:.|.|::......:||:||||||||::||...
  Rat   265 QTVDF---ELSAEETRKSINAWVENKTHGKITNLFDKGTIDPSSVMVLVSAIYFKGQWQNKFQKT 326

  Fly   186 KTRASTFQVTANKSVPVQMMAQMGTFRANYFRDLDAQVIELPYLNSNLSMTIFLPREVEGLSALE 250
            :|..:.|.::..||..|.||.|.|||:..:.::...||:||||.|:.|.|.|.||.....::.:|
  Rat   327 ETVKAPFHISVGKSAVVDMMYQTGTFKLAFIKEPQMQVLELPYANNKLRMIILLPVGTASVNQIE 391

  Fly   251 EKIVG-----FARP--LVAKEVYLKLPKFKIEFRDELKETLEKLGIRELF-TDKSDLSGLFADKS 307
            :.:..     :..|  :|.:.|.:.:|||.:..:.:|...|:.||:.::| ..|:||||:..||
  Rat   392 KHLNAKMLREWTSPSNMVERVVDVHIPKFSLSVKYDLNTLLKSLGMSDIFNVAKADLSGMSPDK- 455

  Fly   308 GGKVSQVSHKAFLEVNEEGAEAAGATSVAVT-NRAGFSTFLMADHPFAFVIRDA-NTIYFQGRVV 370
            |..:|:|.||::::|||||.|||.||...:: .|...:....|:.||.|.|.|. ..|.|.|:..
  Rat   456 GLYLSKVVHKSYVDVNEEGTEAAAATGETISVKRLPVTVQFTANCPFLFFIWDEFYNILFAGKFA 520

  Fly   371 SP 372
            ||
  Rat   521 SP 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	118/381 (31%)
Serpinb11	XP_006249694.2	SERPIN	138..522	CDD:294093	119/390 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm12319
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.830