DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and LOC299277

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	XP_008763124.2	Gene:	LOC299277 / 299277	RGDID:	1595900	Length:	420	Species:	Rattus norvegicus

Alignment Length:	385	Identity:	106/385 - (27%)
Similarity:	177/385 - (45%)	Gaps:	36/385 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VTSVACQTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSAL--GLPSEDKE 72
            :.|:....:..:|:.|:..:.|:|:..||:||...|:.:.:||:|:|.:|:...|  .|....:.
  Rat    47 LASINTDFAFSLYKELALKNPNKNIAFSPLSISAALASLSLGAKGNTLQEILEGLKFNLTETTEI 111

  Fly    73 AVAARYGALLNDL-----QGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNG 132
            .:...|..||..|     |||     :..||.::|.....:...:....:..:::|..:......
  Rat   112 DIHQNYRDLLQRLSQPGGQGQ-----ISRANLLFVEKHLQILNGFKEKAKALYQTEVFATDFQQT 171

  Fly   133 PVAAERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTAN 197
            ..|.:.||.:|:.|:.||||.|:.  .:......:::|.:.|.|||...|||..|....|.:.:.
  Rat   172 CEARKFINDYVMIQSQGKIKEMVT--ELEERTSIVMLNFLLFTGQWSVPFDPDDTFMGKFILDSR 234

  Fly   198 KSVPVQMMAQMGTFRANYFRD--LDAQVIELPYLNSNLSMTIFLP-----REVEGLSALE----E 251
            :.|.|.|| :.......||.|  |...|:||.|.....:|.| ||     .:||  ::|.    .
  Rat   235 RPVKVLMM-KTEDLTTPYFWDEELKCTVVELNYKGHGKAMFI-LPDQGKMEQVE--ASLHPGTLR 295

  Fly   252 KIVGFARPLVAKEVYLKLPKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGKVSQVSH 316
            |.....:|.:..|  |.||||.:....:|:..|.:|||.::|..::||||: |.....:|||:.|
  Rat   296 KWTDSLKPRIIDE--LHLPKFSLSKTYKLENILPELGIMDVFNTQADLSGI-AGAKDVRVSQMIH 357

  Fly   317 KAFLEVNEEGAEAAGATSVAVTNRAG--FSTFLMADHPFAFVIRDANT--IYFQGRVVSP 372
            ...|.:.|.|.||...|.|....|..  ..||:.....|.:::.:.|:  |.|..:|::|
  Rat   358 NTVLGMAETGTEAEATTRVEYNFRPAKLNDTFVNFVRKFLYMVLEPNSELISFMRKVINP 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	103/374 (28%)
LOC299277	XP_008763124.2	serpinA3_A1AC	37..417	CDD:381019	105/383 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010