DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn42Dd and Serpina3m

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001257911.1	Gene:	Serpina3m / 299276	RGDID:	735068	Length:	419	Species:	Rattus norvegicus

Alignment Length:	384	Identity:	118/384 - (30%)
Similarity:	193/384 - (50%)	Gaps:	31/384 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LWVTSVACQTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSAL--GLPSED 70
            |.:.|:....:..:|::|:..:.::|:|.||:||...|::|.:||:|:|.:|:...|  .|....
  Rat    45 LTLESINTDFAFSLYKMLALKNPDKNVVFSPLSISAALAIVSLGAKGNTLEEILEVLRFNLTESY 109

  Fly    71 KEAVAARYGALLNDLQGQEEGPILKL--ANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGP 133
            :..:...:|.||..|  .:.|..:|:  .|.::::....:...:....|..::.||.:.......
  Rat   110 ETDIHQGFGHLLQRL--SQPGDQVKIITGNALFIDKNLQVLAEFQEKTRALYQVEAFTADFQQPR 172

  Fly   134 VAAERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANK 198
            |..:.||.:|.:||.|||:.::  ..:......:|||.:.|:|:|:..|||..|..|.|.|...:
  Rat   173 VTEKLINDYVRNQTQGKIQELV--SGLKERTSMVLVNYLLFRGKWKVPFDPDYTFESEFYVDEKR 235

  Fly   199 SVPVQMMAQMGTFRANYFRD--LDAQVIELPYLNSNLSMTIFLP-----REVEGLSALE--EKIV 254
            ||.|.|| ::......||||  |...|:||.| ..|.|....||     ::||.....|  :|..
  Rat   236 SVKVSMM-KIEELTTPYFRDEELSCSVLELKY-TGNSSALFILPDKGRMQQVEASLQPETLKKWK 298

  Fly   255 GFARPLVAKEVYLKLPKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGK---VSQVSH 316
            ...||....|:|  ||:..|.....|:|.|.:||||::|:.::|||.:    :|.|   ||||.|
  Rat   299 DSLRPRKIDELY--LPRLSISTDYSLEEVLPELGIRDVFSQQADLSRI----TGAKDLSVSQVVH 357

  Fly   317 KAFLEVNEEGAEAAGATSVAVTNRAGFSTFLM-ADHPFAFVIRDAN--TIYFQGRVVSP 372
            |..|:|||.|.|||.||...:..|:|....:: .:.||...:...:  ||.|..:|::|
  Rat   358 KVVLDVNETGTEAAAATGANLVPRSGRPPMIVWFNRPFLIAVSHTHGQTILFMAKVINP 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	114/371 (31%)
Serpina3m	NP_001257911.1	SERPIN	56..416	CDD:214513	115/371 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010