DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and Serping1

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_954524.1	Gene:	Serping1 / 295703	RGDID:	735225	Length:	504	Species:	Rattus norvegicus

Alignment Length:	384	Identity:	101/384 - (26%)
Similarity:	172/384 - (44%)	Gaps:	65/384 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SKEIYQLLS---KSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLPSEDKEAVAARYG 79
            |.::|...|   |:.|  |:..||.||.::|:.|.:||..||...|:..|..|.:        :.
  Rat   155 SVKLYHAFSATKKAET--NMAFSPFSIASLLTQVLLGAGDSTKSNLEDILSYPKD--------FA 209

  Fly    80 ALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISL---------TNGPVA 135
            .:...|:......:..::...:..|         ||:|:.:.:  .|:||         .:|...
  Rat   210 CVHQTLKAFSSKGVTSVSQIFHSPD---------LAIRDTYVN--ASLSLYGSSPRVLGPDGDAN 263

  Fly   136 AERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSV 200
            .:.||.||.:.|:.||..::|  |:.||.:.:|:||:|...:|:..|:..|..||.  :..|..:
  Rat   264 LKLINTWVAENTNHKINELLD--SLPSDTRLVLLNAVYLSAKWKKTFEQKKMMASF--LYKNSMI 324

  Fly   201 PVQMMAQMGTFRANYFRD--LDAQVIELPYLNSNLSMTIFLPRE-VEGLSALEEKIVGFARPLVA 262
            .|.|::.. .:....|.|  |.|:|.:| .|:.|||..|.:|:. ...|..:|:.:    .|.|.
  Rat   325 KVPMLSSK-KYPLALFNDQTLKAKVGQL-QLSHNLSFVIMVPQSPTHQLEDMEKAL----NPTVF 383

  Fly   263 KEV------------YLKLPKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGKVSQVS 315
            |.:            |:.:|:.|::...::...:|||...: ||...:|.||..|.. .:||.:.
  Rat   384 KAILKKLELSKFQPTYVMMPRIKVKSSQDMLSIMEKLEFFD-FTYDLNLCGLTEDPD-LQVSSMK 446

  Fly   316 HKAFLEVNEEGAEAAGATSVAVTNRAGFSTFLMADHPFAFVIRDANTIY--FQGRVVSP 372
            |:..||:.|.|.|||.|::::|....   .......||.|::.|....:  |.|||..|
  Rat   447 HETVLELTETGVEAAAASTISVARNL---LIFEVQQPFLFLLWDQRHKFPVFMGRVYDP 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	98/379 (26%)
Serping1	NP_954524.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	23..75
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	94..132
		SERPIN	150..499	CDD:294093	98/379 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010