DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and Serpinb6a

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	XP_006253933.1	Gene:	Serpinb6a / 291085	RGDID:	735108	Length:	400	Species:	Rattus norvegicus

Alignment Length:	371	Identity:	136/371 - (36%)
Similarity:	208/371 - (56%)	Gaps:	23/371 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 EIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLPSEDKEA------VAARY 78
            ::.:.||:..:| |:.:||:||...|:||||||:|.||.::...|.|   ||.:      |...:
  Rat    35 KLLKTLSEDSSN-NIFLSPISISAALTMVFMGAKGMTASQMVQTLSL---DKCSGNGGGDVHQGF 95

  Fly    79 GALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLT-NGPVAAERINQW 142
            .:||.::.......:||.|||::......:..::..|.|:.:::|.|.:... :...:.:|||.|
  Rat    96 QSLLAEVNKTGTQYLLKTANRLFGEKTCDILASFKDACRKFYEAEMEELDFKGDTEQSRQRINTW 160

  Fly   143 VLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMAQ 207
            |..:|..|||.::.||.:..|...:|||||||||.|:.:|:...||...|:|:..:..|||||..
  Rat   161 VAKKTEDKIKELLAPGIVDPDTVLVLVNAIYFKGNWDKQFNKEHTREKPFKVSKTEEKPVQMMFM 225

  Fly   208 MGTFRANYFRDLDAQVIELPYLNSNLSMTIFLPREVEGLSALE-----EKIVGFAR--PLVAKEV 265
            ..||:..|..::..:::.|||..:.|:|.|.||.|...|..:|     ||.:.:.|  .|..:||
  Rat   226 KSTFKMTYIGEIFTKILLLPYAGNELNMIIMLPDEHIELKTVEKELTYEKFIEWTRLDMLDEEEV 290

  Fly   266 YLKLPKFKIEFRDELKETLEKLGIRELFTD-KSDLSGLFADKSGGKVSQVSHKAFLEVNEEGAEA 329
            .:.||:||:|...::|..|.|||:.:.|.: ::|.||: |.|.|..:|:|.||||:||||||.||
  Rat   291 EVFLPRFKLEENYDMKVVLGKLGMTDAFMEGRADFSGI-ASKQGLFLSKVIHKAFVEVNEEGTEA 354

  Fly   330 AGATSVAVTNRA-GFSTFLMADHPFAFVIRDANT--IYFQGRVVSP 372
            ..||...:|.|. .|:...:|||||.|.|:...|  |.|.||..||
  Rat   355 VAATGSTITMRCLRFTPRFLADHPFLFFIQHVKTKGILFCGRFSSP 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	133/366 (36%)
Serpinb6a	XP_006253933.1	SERPIN	25..400	CDD:294093	134/369 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm12319
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.730