Protein Alignment Spn42Dd and SERPINA11

DIOPT Version :10

• Sequence 1: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001073920.1
• Gene: SERPINA11 / 256394
• HGNCID: 19193
• Length: 422
• Species: Homo sapiens
• Alignment Length: 380
• Identity: 102/380 - (26%)
• Similarity: 196/380 - (51%)
• Gaps: 31/380 - (8%)

  Fly    10 VTSVACQTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLP-SEDKEA 73
            :|:.|.:..||:     .:....|:..|||||.|.|:::.:||:.:|:..:...||.. :|..||
Human    54 ITNFALRLYKEL-----AADAPGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEA 113

  Fly    74 -VAARYGALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAAE 137
             :...:.:||:.|........||:.|.::::.:....|:|..:::|.:.:.|.|.:.|:......
Human   114 DIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGR 178

  Fly   138 RINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKT-RASTFQVTANKSVP 201
            :||.::..||.|::...:.  ..:.|...:|.|.|:||.:|:..|...:| :..:|.|....|:.
Human   179 QINDYLRRQTYGQVVDCLP--EFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQ 241

  Fly   202 VQMMAQMGTFRANYFRDLDAQVIELPYLNSNLSMTIFLP-----REVEGLSALE-EKIVGFARPL 260
            |.||.|....|..|.:||...|:::.|..:.|::.: ||     ::||  :||: :.:..:.:.|
Human   242 VPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLV-LPDPGKMKQVE--AALQPQTLRKWGQLL 303

  Fly   261 VAKEVYLKLPKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGKVSQVSHKAFLEVNEE 325
            :...:.|.||:|.|.....|::.|.::|:..:...::|.||: ..:....:|:|||||.::::|:
Human   304 LPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGV-TGQLNKTISKVSHKAMVDMSEK 367

  Fly   326 GAEAAGATSVAVTNRAGFSTFLMAD------HPFAFVIRDANT--IYFQGRVVSP 372
            |.| |||.|..::.....:|  |:|      .||..::.:..|  :.|.|:||:|
Human   368 GTE-AGAASGLLSQPPSLNT--MSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNP 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	serpin42Dd-like_insects	12..372	CDD:381070	100/376 (27%)
SERPINA11	NP_001073920.1	serpinA11	50..422	CDD:381025	102/380 (27%)