DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn42Dd and Serpina3c

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_036789.2	Gene:	Serpina3c / 24794	RGDID:	2972	Length:	416	Species:	Rattus norvegicus

Alignment Length:	383	Identity:	122/383 - (31%)
Similarity:	197/383 - (51%)	Gaps:	28/383 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LWVTSVACQTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSAL--GLPSED 70
            |.:.|:....:..:|:.|:..:.::|:|.||:||...|:::.:||:.||.:|:...|  .|....
  Rat    43 LTLASINTDFTLSLYKKLALRNPDKNVVFSPLSISAALAILSLGAKDSTMEEILEGLKFNLTEIT 107

  Fly    71 KEAVAARYGALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVA 135
            :|.:...:|.||..|...|:...:...:.::::.:..:...:....|..:::||..........|
  Rat   108 EEEIHQGFGHLLQRLSQPEDQAEINTGSALFIDKEQPILSEFQEKTRALYQAEAFVADFKQCNEA 172

  Fly   136 AERINQWVLDQTSGKIKGMI-DPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKS 199
            .:.||.:|.:||.|||..:. |....||.|   |||.:.|||:|:..|:|..|..|.|.:...:|
  Rat   173 KKFINDYVSNQTQGKIAELFSDLDERTSMV---LVNYLLFKGKWKVPFNPNDTFESEFYLDEKRS 234

  Fly   200 VPVQMMAQMGTFRANYFRD--LDAQVIELPYLNSNLSMTIFLP-----REVEGLSALE----EKI 253
            |.|.|| ::......|.||  |...|:||.| ..|.|....||     ::||  |:|:    :|.
  Rat   235 VKVPMM-KIKDLTTPYVRDEELSCSVLELKY-TGNASALFILPDQGKMQQVE--SSLQPETLKKW 295

  Fly   254 VGFARPLVAKEVYLKLPKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGKVSQVSHKA 318
            ....||.:..|  |::|||.|.....|:|.|.:||||::|:.::|||.:...|: ..||||.|||
  Rat   296 KDSLRPRIISE--LRMPKFSISTDYNLEEVLPELGIRKIFSQQADLSRITGTKN-LHVSQVVHKA 357

  Fly   319 FLEVNEEGAEAAGATSVAVTNRAGFST--FLMADHPFAFVIRDAN--TIYFQGRVVSP 372
            .|:|:|.|.|.|.||:|....::...|  .|..:.||..||.|.|  :::|.|:|.:|
  Rat   358 VLDVDETGTEGAAATAVTAALKSLPQTVPLLNFNRPFMLVITDNNGQSVFFMGKVTNP 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	118/370 (32%)
Serpina3c	NP_036789.2	SERPIN	54..415	CDD:214513	119/370 (32%)
Serpina3c	NP_036789.2	RCL	365..392		8/26 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010