DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and Serpina3j

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001094942.1	Gene:	Serpina3j / 238395	MGIID:	2182843	Length:	420	Species:	Mus musculus

Alignment Length:	389	Identity:	117/389 - (30%)
Similarity:	186/389 - (47%)	Gaps:	40/389 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LWVTSVACQTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLP-SEDK 71
            |.:.|:....:..:|:.|:..:.::|.|.||:||...|:.:.:||:|:|.:|:...|... :|..
Mouse    45 LTLASINTDFAFSLYKKLALKNPHKNFVFSPLSITIALASLSLGAKGNTLEEILEGLKFNLTETP 109

  Fly    72 EA-VAARYGALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVA 135
            || :...:|.||..|....:...:...|.:.|.....:...:....|..:.:|..:........|
Mouse   110 EADIHQGFGHLLQRLSQPGDQVQISTGNSMVVEKHLQILAEFKEKARALYHTEVFTADFQQPREA 174

  Fly   136 AERINQWVLDQTSGKIKGMI-DPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKS 199
            .:.:|.:|.:||.|.||.:: |....||.|   :.|...|.|:|...|||.:|...||.......
Mouse   175 RKLLNDYVSNQTQGMIKELVSDLEERTSMV---MTNFALFNGKWNMTFDPYETFMGTFIEDRRTP 236

  Fly   200 VPVQMMAQMGTFRANYFRD--LDAQVIELPYLNSNLSMTIFLP-----REVEGLSALEEKIVGF- 256
            |.|.|| :|...||.||||  :...|:||.|..:..:|.| ||     ::||. |.....:.|:
Mouse   237 VKVSMM-KMKELRAPYFRDEKMKCTVVELNYKGNGKAMFI-LPDQGKMKQVEA-SLQPATLRGWR 298

  Fly   257 --ARPLVAKEVYLKLPKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGK---VSQVSH 316
              .||.:..|:|  ||||.|.....|:..|.:|||:|:|:.::||||:    ||||   ||::.|
Mouse   299 KSLRPRMIDELY--LPKFSISKNYRLENILPELGIKEVFSTQADLSGI----SGGKDVRVSRMFH 357

  Fly   317 KAFLEVNEEGAEAAGATSVAVTNRAGF------STFLMADHPFAFVI--RDANTIYFQGRVVSP 372
            .|.|::.|.|.||...|    .::..|      .|.:..:.||.|.:  .|:..|.|.|::.:|
Mouse   358 SAALDMTETGTEARATT----RDKYDFLSTKSNPTVVNLNTPFLFCVLHSDSENIDFMGKINNP 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	114/376 (30%)
Serpina3j	NP_001094942.1	serpinA3_A1AC	37..417	CDD:381019	116/387 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010