Protein Alignment Spn42Dd and SERPINB1

DIOPT Version :9

• Sequence 1: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_109591.1
• Gene: SERPINB1 / 1992
• HGNCID: 3311
• Length: 379
• Species: Homo sapiens
• Alignment Length: 389
• Identity: 139/389 - (35%)
• Similarity: 212/389 - (54%)
• Gaps: 39/389 - (10%)

  Fly    10 VTSVACQTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLPSEDKEAV 74
            ::|...:.:.:::..||:::...|:.:||.||.:.::|||:|..|:||.:|......  ...|.|
Human     4 LSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF--NTVEEV 66

  Fly    75 AARYGALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAAER- 138
            .:|:.:|..|:..:....|||||||:|....|:....:.::.::.:.::..|:...:....|.:
Human    67 HSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDARKT 131

  Fly   139 INQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQ 203
            |||||..||.|||..::..|.:.:..|.:|||||||||.|:.||....|..:.|::.......|:
Human   132 INQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVK 196

  Fly   204 MMAQMGTFRANYFRDLDAQVIELPYLNSNLSMTIFLPREVE----GLSALE-----EKIVGFARP 259
            ||.|...|...|..||..:|:||||....|||.|.||.::|    ||..:|     ||:..:.:|
Human   197 MMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKP 261

  Fly   260 --LVAKEVYLKLPKFKIEFRDELKETLEKLGIRELF-TDKSDLSGLFADKSGGK---VSQVSHKA 318
              |...||.:.||:||:|....|...|.:||:::|| :.|:||||:    ||.:   :|::.||:
Human   262 ENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGM----SGARDIFISKIVHKS 322

  Fly   319 FLEVNEEGAEAAGATSVAVTNRAGFSTFLM--------ADHPFAFVIR--DANTIYFQGRVVSP 372
            |:||||||.|||.||       ||.:||.|        |||||.|.||  .:.:|.|.||..||
Human   323 FVEVNEEGTEAAAAT-------AGIATFCMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	135/378 (36%)
SERPINB1	NP_109591.1	SERPIN	4..379	CDD:294093	137/387 (35%)
		CARD-binding motif (CBM). /evidence=ECO:0000269|PubMed:30692621	351..379		12/27 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	LDO	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.830