DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn42Dd and Serpinf2

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_032904.1	Gene:	Serpinf2 / 18816	MGIID:	107173	Length:	491	Species:	Mus musculus

Alignment Length:	375	Identity:	114/375 - (30%)
Similarity:	187/375 - (49%)	Gaps:	52/375 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 EIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLPSEDKEAVAARYGALLND 84
            :::.|::::.|:.|||:||:|:...||.:.:||:..|...|...|.:.:          |:.|..
Mouse    92 DLFSLVAQTSTSSNLVLSPLSVALALSHLALGAQNQTLHSLHRVLHMNT----------GSCLPH 146

  Fly    85 LQG---QEEGP-ILKLANRIY------VNDQYSLNQNYNLAVREPFK---SEAESISLTNGPVAA 136
            |..   |..|| .::||.|||      :.|.: |.|:..|...:|.|   .:.|.::
Mouse   147 LLSHFYQNLGPGTIRLAARIYLQKGFPIKDDF-LEQSERLFGAKPVKLTGKQEEDLA-------- 202

  Fly   137 ERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVP 201
             .|||||.:.|.|||:..:  ..:......||:|||:|.|.|.:||||:.|:...|.:....:|.
Mouse   203 -NINQWVKEATEGKIEDFL--SELPDSTVLLLLNAIHFHGFWRTKFDPSLTQKDFFHLDERFTVS 264

  Fly   202 VQMMAQMGTFRANYF--RDLDAQVIELPYLNSNLSMTIFLPREVE-GLSALEEKIVG---FARPL 260
            |.||..: ::...:|  ...:.||...|:.| |:|..:.:|...| .:|.:...:..   :...|
Mouse   265 VDMMHAV-SYPLRWFLLEQPEIQVAHFPFKN-NMSFVVVMPTYFEWNVSEVLANLTWDTLYHPSL 327

  Fly   261 VAKEVYLKLPKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGKVSQVSHKAFLEVNEE 325
            ..:...:.|||..::.:.:|..||.:||::||| ...||.|:  .:....||.|.|::.:|::|.
Mouse   328 QERPTKVWLPKLHLQQQLDLVATLSQLGLQELF-QGPDLRGI--SEQNLVVSSVQHQSTMELSEA 389

  Fly   326 GAEAAGATSVAVTNRAGFSTFLMADHPFAFVIRDANTI---YFQGRVVSP 372
            |.|||.|||||: ||...|:|.: :.||.|.|.: :||   .|.|.|.:|
Mouse   390 GVEAAAATSVAM-NRMSLSSFTV-NRPFLFFIME-DTIGVPLFVGSVRNP 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	112/370 (30%)
Serpinf2	NP_032904.1	alpha2AP	82..433	CDD:239008	112/370 (30%)
Serpinf2	NP_032904.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	439..491
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010