Protein Alignment Spn42Dd and SERPINA3

DIOPT Version :9

• Sequence 1: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001076.2
• Gene: SERPINA3 / 12
• HGNCID: 16
• Length: 423
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 123/370 - (33%)
• Similarity: 183/370 - (49%)
• Gaps: 27/370 - (7%)

  Fly    21 IYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSAL--GLPSEDKEAVAARYGALLN 83
            :|:.|.....::|::.||:||.|.|:.:.:||..:|..|:...|  .|....:..:...:..||.
Human    60 LYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLR 124

  Fly    84 DLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAAERINQWVLDQTS 148
            .|....:...|.:.|.::|.:|.||...:....:..:.|||.:....:...|.:.||.:|.:.|.
Human   125 TLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTR 189

  Fly   149 GKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGTFRA 213
            |||..:|.  .:.|....:|||.|:||.:||..|||..|..|.|.::..|.|.|.||: :.....
Human   190 GKITDLIK--DLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMS-LHHLTI 251

  Fly   214 NYFRD--LDAQVIELPYLNSNLSMTIFLP-----REVEGLSALEEKIVGFARPLVAKEV-YLKLP 270
            .||||  |...|:||.| ..|.|....||     .|||.: .|.|.:..:...|..:|: .|.||
Human   252 PYFRDEELSCTVVELKY-TGNASALFILPDQDKMEEVEAM-LLPETLKRWRDSLEFREIGELYLP 314

  Fly   271 KFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGK---VSQVSHKAFLEVNEEGAEAAGA 332
            ||.|.....|.:.|.:|||.|.||.|:||||:    :|.:   ||||.|||.|:|.|||.||:.|
Human   315 KFSISRDYNLNDILLQLGIEEAFTSKADLSGI----TGARNLAVSQVVHKAVLDVFEEGTEASAA 375

  Fly   333 TSVAVTNRAGF---STFLMADHPFAFVI--RDANTIYFQGRVVSP 372
            |:|.:|..:..   .|.:..:.||..:|  .|...|:|..:|.:|
Human   376 TAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNP 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	121/365 (33%)
SERPINA3	NP_001076.2	serpinA3_A1AC	40..421	CDD:381019	123/370 (33%)
		RCL	369..394		8/24 (33%)
		O-glycosylated at one site	381..389		1/7 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010