DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn42Dd and LOC110439158

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	XP_021329696.1	Gene:	LOC110439158 / 110439158	-ID:	-	Length:	412	Species:	Danio rerio

Alignment Length:	409	Identity:	109/409 - (26%)
Similarity:	199/409 - (48%)	Gaps:	50/409 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IFLWVTS---VACQTSKEIYQ-------------------------LLSKSHTNQNLVVSPVSIE 42
            :|||:..   |.|...:.:.|                         :.|..:.::|:..||.::.
Zfish     6 VFLWICGFAIVVCGNQETLQQPPISAKLPSLININNDFAFHLYKRLIESPDYQSKNIFFSPFTVS 70

  Fly    43 TILSMVFMGAEGSTAKELQSALGLPSE--DKEAVAARYGALLNDLQGQEEGPILKLANRIYVNDQ 105
            ..||.:.:||.|.|.::|.|.:|..|.  ..|.:...:.:||.|: |...|..:.:...:|.:|:
Zfish    71 MALSKLTLGAGGDTKQQLLSGIGYNSAIFSTEEMHQLFHSLLEDI-GNRTGVDIDIGTALYASDR 134

  Fly   106 YSLNQNYNLAVREPFKSEAESISLTNGPVAAERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVN 170
            :..:..:...::|.:.::..::.. ......::||::|.::|.|||...:|  .:..|....|:.
Zfish   135 FKPHSKFLEDMKEFYHTDGFTVDF-RVKETVDQINKYVEEKTHGKINQAVD--DLEKDTLMFLLT 196

  Fly   171 AIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGTFRANYFRDLDAQVIELPYLNSNLSM 235
            .|||||:|:..|:|.||..|||.:....:||||||.|....:..|..:|..:|:.|.| |.:.||
Zfish   197 YIYFKGKWDKPFNPEKTCESTFHIDDKTTVPVQMMHQYEYLKVYYDAELSIKVLCLDY-NDSFSM 260

  Fly   236 TIFLPREVEGLSALEEKIVGFARPLVAK--------EVYLKLPKFKIEFRDELKETLEKLGIREL 292
            .:.:|....|...:|:..:..:|..:.|        :|.:.:||..::....|.:.|:.:|:.::
Zfish   261 FLAVPDVHMGRKTIEDLEMTISRQHIEKWKRSAFERKVDIYVPKLSLKTSYFLNDILKGMGMADM 325

  Fly   293 FTDKSDLSGLFADKSGGKVSQVSHKAFLEVNEEGAEAAGATSVAVTNRAGFS--TFLMADHPFAF 355
            |:||:|.:|:..:|.  .:|:|.|||.|:::|:|..||..|:|.. .:..:|  :.|..|.||..
Zfish   326 FSDKADFTGVSEEKI--FISKVVHKATLDIDEKGTTAAAVTTVQF-RQLSYSPLSTLSFDRPFMI 387

  Fly   356 VIRDA--NTIYFQGRVVSP 372
            .|.|.  :.|.|.|:||:|
Zfish   388 FITDQTNDNILFFGKVVNP 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	101/391 (26%)
LOC110439158	XP_021329696.1	alpha-1-antitrypsin_like	40..403	CDD:239011	100/370 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020