DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and LOC100909605

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	XP_006240581.2	Gene:	LOC100909605 / 100909605	RGDID:	6502633	Length:	410	Species:	Rattus norvegicus

Alignment Length:	384	Identity:	122/384 - (31%)
Similarity:	185/384 - (48%)	Gaps:	34/384 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 TSVACQT--SKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSAL--GLPSEDK 71
            |..:|.|  :..:|:.|...:.::|:|.|..||.|.|.::.:||:.:|.||:...|  .|....:
  Rat    36 TLSSCNTDFAFSLYKELVLKNPDKNIVFSSFSISTALVLLSLGAKNNTLKEILEGLKFNLTETPE 100

  Fly    72 EAVAARYGALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAA 136
            ..:...|..||..|....:...:...:.:::.....:...:....|..:::||.|........|.
  Rat   101 AEIHQGYEHLLQRLNLPGDQVQISTGSALFIKKHLQILAEFQEKARALYQAEAFSTDFQQPHEAK 165

  Fly   137 ERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVP 201
            :.||.:|..||.||||.:|  ..:......:|||.|||||:|:..|||..|..|.|.:...|||.
  Rat   166 KLINDYVRKQTQGKIKELI--SVLDKKTSMVLVNYIYFKGKWKMPFDPHDTFQSEFYLDEKKSVK 228

  Fly   202 VQMMAQMGTFRANYFRD--LDAQVIELPYLNSNLSMTIFLP-----REVEGLSALEEKIV----G 255
            |.|| ::......||||  |...|:||.| ..|.|....||     ::||  ::|:.:.:    .
  Rat   229 VPMM-KIEKLTTPYFRDEELSCSVLELKY-TGNASALFILPDQGRMQQVE--ASLQPETLRRWKD 289

  Fly   256 FARPLVAKEVYLKLPKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGK---VSQVSHK 317
            ..||....|  |::|||.|.....|.:.|.:|||||:|:.::|||.:    :|.|   ||||.||
  Rat   290 TLRPRRIDE--LRMPKFSISTDMRLGDILPELGIREVFSQQADLSRI----TGAKDLSVSQVVHK 348

  Fly   318 AFLEVNEEGAEAAGATSVAVTNRAG--FSTFLMADHPFAFVIRDANT--IYFQGRVVSP 372
            |.|:|.|.|.|||.||.|.:.....  :...:..:.||..:|.|.||  ..|..:|.:|
  Rat   349 AVLDVTETGTEAAAATGVKIIPMCAKFYYVTMYFNRPFLMIISDTNTHIALFMAKVTNP 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	118/374 (32%)
LOC100909605	XP_006240581.2	alpha-1-antitrypsin_like	41..404	CDD:239011	118/374 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010