DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and serpine1

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001108031.1	Gene:	serpine1 / 100136840	ZFINID:	ZDB-GENE-070912-60	Length:	384	Species:	Danio rerio

Alignment Length:	384	Identity:	109/384 - (28%)
Similarity:	191/384 - (49%)	Gaps:	26/384 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LCIFLWVTSVAC------QT--SKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKEL 60
            |.||....|..|      ||  ..:::....:|..::||.:||..|.::|.|..|||.|:|.|.|
Zfish     7 LLIFALCASSLCNLIQDKQTDFGLQVFAEAVQSAPDRNLALSPYGIASVLGMAQMGAYGATLKLL 71

  Fly    61 QSALGLPSEDKEAVAARYGALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAE 125
            .|.:|...::: .:......|..|| ..|:|  :::|:.:.|:.:..|.:.:..::.:.|:|...
Zfish    72 ASKMGYSLQER-GMPKLQRLLQRDL-ASEDG--VEVASGVMVDRKIILEKVFRRSLSKAFQSVPH 132

  Fly   126 SISLTNGPVAAERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRAS 190
            .|..:...:|.:.||.|..|.|.|.|...:..|.::...:.:.:||::|.|.|::.|||..||..
Zfish   133 QIDFSQPEMARQVINSWTSDHTDGMISEFLPSGVLSELTRLVFLNALHFHGVWKTPFDPRNTREQ 197

  Fly   191 TFQVTANKSVPVQMMAQMGTFRANYF--RD-LDAQVIELPYLNSNLSMTIFLPREVE-GLSALEE 251
            .|......:|.|.||.....|....|  :| :|..|||:||...::||.:..|.|.: .||||.:
Zfish   198 LFHTVNGSAVSVPMMTTTQKFNYGEFVSKDGVDYDVIEMPYEGESISMLLVTPFEKDVPLSALNK 262

  Fly   252 -----KIVGFARPLVAKEVYLKLPKFKIEFRDELKETLEKLGIRELFT-DKSDLSGLFADKSGGK 310
                 :|..:.:.:......|.:|:|.::...:||.||.::|:.::|: .::|.|.:..::. ..
Zfish   263 ELSSSRIHQWRQEMRKISKQLSIPRFSMDTEIDLKSTLSRMGLGDIFSQSRADFSRITTEEP-LC 326

  Fly   311 VSQVSHKAFLEVNEEGAEAAGATSVAVTNRAGFSTFLMADHPFAFVIRDANT--IYFQG 367
            ||:|..:..|||||||.:.:.||:..:.:|.......: |.||.|:|:...|  :.|.|
Zfish   327 VSKVLQRVKLEVNEEGTKGSSATAAVIYSRMAVEEITL-DRPFFFLIQHKPTGALLFSG 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	104/366 (28%)
serpine1	NP_001108031.1	SERPIN	26..384	CDD:294093	102/363 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020