Protein Alignment Spn28F and SERPINB7

DIOPT Version :9

• Sequence 1: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_001035237.1
• Gene: SERPINB7 / 8710
• HGNCID: 13902
• Length: 380
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 103/377 - (27%)
• Similarity: 190/377 - (50%)
• Gaps: 27/377 - (7%)

  Fly    12 SVSCRFADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLKL---------P 67
            :.:..|..:.::.:.......|:..|.||:..||::..:||:..:..::..:|.:         .
Human     6 AANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHVNTASGYGNSS 70

  Fly    68 DDKKEVAAKYKDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDP- 131
            :.:..:.::.|.:.|.:....|...||:.|.::..|.:.....|.:..:..:.|:.|.:|..:.
Human    71 NSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEKLYDAKVERVDFTNHL 135

  Fly   132 NKASSIVNNWVDNQTRGKIKDLVSSNDMSKMELIVL-NAIYFKGQWEYKFNPKLTKKRNFRVSDQ 195
            ......:|.||:|:|.||||:::....:|...::|| ||:||||:|:..|....|...:|:....
Human   136 EDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGKWQSAFTKSETINCHFKSPKC 200

  Fly   196 KSVPVEMMSLFQSFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVDGLSELEKKIVGFK----- 255
            ....|.||...:.|..:...:...||:||.| |..::|.:.||:  :.|||:|.|:. |:
Human   201 SGKAVAMMHQERKFNLSVIEDPSMKILELRY-NGGINMYVLLPE--NDLSEIENKLT-FQNLMEW 261

  Fly   256 ---PKLSKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAFEKS-ADFKDLVENSNVHVKKVIHKAF 316
               .:::...|.:..|:||||...::.:.|.|:|::|.|::| ||...:.....:::.:::||::
Human   262 TNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGLKDIFDESKADLSGIASGGRLYISRMMHKSY 326

  Fly   317 IEVNEEGAEAAAATALLFVRYSMPMPSSQMVFNADHPFAYVIRDRETIYFQG 368
            |||.|||.||.|||....|...:|..:   :|.|||||.:|||..:.|.|.|
Human   327 IEVTEEGTEATAATGSNIVEKQLPQST---LFRADHPFLFVIRKDDIILFSG 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	103/375 (27%)
SERPINB7	NP_001035237.1	serpinB7_megsin	1..380	CDD:381032	103/377 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	221	1.000	Domainoid score	I2614
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3541
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.980