DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28F and SRP3

DIOPT Version :9

Sequence 1:	NP_524957.2	Gene:	Spn28F / 49807	FlyBaseID:	FBgn0028987	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_176586.1	Gene:	SRP3 / 842706	AraportID:	AT1G64030	Length:	385	Species:	Arabidopsis thaliana

Alignment Length:	386	Identity:	110/386 - (28%)
Similarity:	181/386 - (46%)	Gaps:	85/386 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 NNLISSPLSVEIALSMAYMG-------------ARAKTAQEMRNVLKLPDDKKEVAA-KYKDLLS 82
            :|:|.||.|:..|::|...|             .|:.:..|::.|.      :|:|: .|.|  .
plant    29 SNVIFSPASINSAITMHAAGPGGDLVSGQILSFLRSSSIDELKTVF------RELASVVYAD--R 85

  Fly    83 KLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDI-VDPNKASSIVNNWVDNQT 146
            ...|..|:   :.||.::::|.....|.:..:.::.|.|....:|. .:..:....||:||::.|
plant    86 SATGGPKI---TAANGLWIDKSLPTDPKFKDLFENFFKAVYVPVDFRSEAEEVRKEVNSWVEHHT 147

  Fly   147 RGKIKDLVSSNDMSKM-ELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVPVEMMSLFQS-F 209
            ...||||:....::.: ..|..||:.|||.|:..|....|:..:|.:.:..||.|..||.::: :
plant   148 NNLIKDLLPDGSVTSLTNKIYANALSFKGAWKRPFEKYYTRDNDFYLVNGTSVSVPFMSSYENQY 212

  Fly   210 RAAHDSELGAKIIELPYR------NSSLSMLIFLPDQVDGLSELEKKIVG-----------FKPK 257
            ..|:|   |.|::.|||:      |...||..:|||:.|||.:|.:|:..           ::.:
plant   213 VRAYD---GFKVLRLPYQRGSDDTNRKFSMYFYLPDKKDGLDDLLEKMASTPGFLDSHIPTYRDE 274

  Fly   258 LSKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAFEKSADFKDLVENSNVHVKKVIHKAFIEVNEE 322
            |.|    .|:|||||||...:..||..:|::.                   ..:.|||.:|::||
plant   275 LEK----FRIPKFKIEFGFSVTSVLDRLGLRS-------------------MSMYHKACVEIDEE 316

  Fly   323 GAEAAAATA-------LLFVRYSMPMPSSQMVFNADHPFAYVIRDRE--TIYFQGHFVKPN 374
            |||||||||       |.||.     |..::.|.|||||.::||:.:  |:.|.|....|:
plant   317 GAEAAAATADGDCGCSLDFVE-----PPKKIDFVADHPFLFLIREEKTGTVLFVGQIFDPS 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	109/380 (29%)
SRP3	NP_176586.1	serpinP_plants	8..371	CDD:381001	109/383 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	172	1.000	Domainoid score	I1138
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H76659
Inparanoid	1	1.050	172	1.000	Inparanoid score	I1521
OMA	1	1.010	-	-		QHG57242
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1112
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.070