DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28F and Serpina7

DIOPT Version :9

Sequence 1:	NP_524957.2	Gene:	Spn28F / 49807	FlyBaseID:	FBgn0028987	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_112390.1	Gene:	Serpina7 / 81806	RGDID:	619833	Length:	426	Species:	Rattus norvegicus

Alignment Length:	379	Identity:	102/379 - (26%)
Similarity:	180/379 - (47%)	Gaps:	23/379 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SVSCRFADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVL--KLPDDK-KEV 73
            |::..||...|:.|:.||...|:..||:|:..||:|...|:.:.|..::..||  .|.|.. ||:
  Rat    55 SINADFAFRLYRKLSVENPDLNIFFSPVSISAALAMLSFGSGSSTQTQILEVLGFNLTDTPVKEL 119

  Fly    74 AAKYKDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDPNKASSIV 138
            ...::.|:..|........|.:.|.:::.::.:.:..:...||..:..|..:.|..:.:.|...:
  Rat   120 QQGFQHLICSLNFPNNELELQMGNAVFIGQQLKPLAKFLDDVKTLYETEVFSTDFSNVSAAQHEI 184

  Fly   139 NNWVDNQTRGKIKDLVSSNDMSKMELIVLNAIYFKGQWEYKFN-PKLTKKRNFRVSDQKSVPVEM 202
            |::|:.||:|||..|:....:: :.:|::|.|:||.||...|. .|..:..||.|....:|.|.|
  Rat   185 NSYVEKQTKGKIVGLIQDLKLN-IIMILVNYIHFKAQWANPFRVSKTEESSNFSVDKSTTVQVPM 248

  Fly   203 MSLFQSFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVDGLSE------LEKKIVGFKPKLSKM 261
            |...:.:....|.||...::::.|..::|::.: ||.  :|..|      ..|.:..:...|.|.
  Rat   249 MHQLEQYYHYVDVELNCTVLQMDYSANALALFV-LPK--EGHMEWVEAAMSSKTLKKWNHLLQKG 310

  Fly   262 DVTLRLPKFKIEFFAQLNKVLVAMGIQDAFEKSADFKDLVENSNVHVKKVIHKAFIEVNEEGAEA 326
            .|.|.:|||.|.....|...|..||::|||.:||||..:.:::.:.:....|||.:.:.|||.:.
  Rat   311 WVELFVPKFSISATYDLGSTLQKMGMRDAFAESADFPGITKDNGLKLSYAFHKAVLHIGEEGTKE 375

  Fly   327 AAATALLFVRYSMPMPS---SQMVFNADHPFAYVIRDRET--IYFQGHFVKPNE 375
            .|:..    ..|:..|.   ...|...|..|..:|.::.|  :.|.|..|.|.:
  Rat   376 GASPE----AGSLDQPEVAPLHAVIRLDRTFLLMILEKRTRSVLFLGKVVDPTK 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	99/370 (27%)
Serpina7	NP_112390.1	serpinA7_TBG	48..425	CDD:381023	102/377 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010