DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28F and Serpina9

DIOPT Version :9

Sequence 1:	NP_524957.2	Gene:	Spn28F / 49807	FlyBaseID:	FBgn0028987	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_001348839.1	Gene:	Serpina9 / 71907	MGIID:	1919157	Length:	418	Species:	Mus musculus

Alignment Length:	384	Identity:	116/384 - (30%)
Similarity:	199/384 - (51%)	Gaps:	27/384 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 ATSVS---CRFADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLK-----L 66
            |:.||   .||:...||.||:||...|::.||:|:..:|:|..:|||:.|..::...|.     :
Mouse    43 ASQVSPSNTRFSFLLYQRLAQENPGQNILFSPVSISTSLAMLSLGARSATKTQILRTLGFNFTWV 107

  Fly    67 PDDKKEVAAKY--KDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIV 129
            .:....:..:|  :.|....:|||    |.:.:.:::.|:.||..::...||..:.|:..:.|..
Mouse   108 SEPTIHMGFEYLVRSLNKCHQGRE----LRMGSVLFIRKELQLQATFLDRVKKLYGAKVFSEDFS 168

  Fly   130 DPNKASSIVNNWVDNQTRGKIKDLVSSNDMSKMELIVLNAIYFKGQWEYKFNPKLTKKR-NFRVS 193
            :...|.:.:|::|:.:|:||:.|::...| |:..::::|.|:||..|...|:...|.|. .|.:|
Mouse   169 NAATAQAQINSYVEKETKGKVVDVIQDLD-SQTAMVLVNHIFFKANWTQPFSTANTNKSFPFLLS 232

  Fly   194 DQKSVPVEMMSLFQSFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVDGLSELEKKIVG----- 253
            ...:|.|.||...:||....|.|||..|:::.||..:::..: ||.: ..:.:|||.:..
Mouse   233 KGTTVHVPMMHQTESFAFGVDKELGCSILQMDYRGDAVAFFV-LPGK-GKMRQLEKSLSARRLRK 295

  Fly   254 FKPKLSKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAFEKSADFKDLVENSNVHVKKVIHKAFIE 318
            :...|.|..:.:.:|||.|.....|..:|..|||:|||..:|||..:.:...:.|.|..|||.::
Mouse   296 WSRSLQKRWIKVFIPKFSISASYNLETILPKMGIRDAFNSNADFSGITKTHFLQVSKAAHKAVLD 360

  Fly   319 VNEEGAEAAAATALLFVRYSMPMPSSQMVFNADHPFAYVIRDR--ETIYFQGHFVKPNE 375
            |:|||.||||||....:..|...|||.:.|.  .||..::.|:  |::.|.|....|.:
Mouse   361 VSEEGTEAAAATTTKLIVRSRDTPSSIIAFK--EPFLILLLDKNTESVLFLGKVENPRK 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	113/373 (30%)
Serpina9	NP_001348839.1	alpha-1-antitrypsin_like	49..412	CDD:239011	112/371 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020