Protein Alignment Spn28F and Serpinb12

DIOPT Version :10

• Sequence 1: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_082247.1
• Gene: Serpinb12 / 71869
• MGIID: 1919119
• Length: 423
• Species: Mus musculus
• Alignment Length: 422
• Identity: 132/422 - (31%)
• Similarity: 217/422 - (51%)
• Gaps: 62/422 - (14%)

  Fly    11 TSVSCRFADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVL----------K 65
            |:.:.:|..||::.::|::|..|:...|||:..|..|..:|||..:|.::...|          |
Mouse     5 TAANNKFCFDFFREISKDDAHKNIFVCPLSLSAAFGMVRLGARGDSAHQIDEALHFNELSKDEHK 69

  Fly    66 LPDD----------------KKEVAAK-----------------YKDLLSKLEGREKVATLSLAN 97
            .|:|                :|:.:|.                 :..|||:::..:...|||:||
Mouse    70 EPNDPSPQSESKASDSSLEGQKQTSASQDQQGESTNDHQLLGCHFGKLLSRIDRDKSYYTLSMAN 134

  Fly    98 RIYVNKKFQLVPSYNQMVKDSFMAEAEAIDI-VDPNKASSIVNNWVDNQTRGKIKDLVSSNDMSK 161
            |:|..::|.:...|:..|.:.|....|::|. .|..|:...:|.||::|::||||:|.....:..
Mouse   135 RLYGEQEFPICSEYSDDVTEFFHTTVESVDFQKDSEKSRQEINFWVESQSQGKIKELFGKEAIDN 199

  Fly   162 MELIVL-NAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVPVEMMSLFQSFRAAHDSELGAKIIELP 225
            ..::|| ||:|||.:||.:||.:.|...:|.:::.:...|:||:....||.....||.|:|:|:.
Mouse   200 STVLVLVNAVYFKAKWEREFNSENTVDASFCLNENEKKTVKMMNQKGKFRIGFIDELQAQILEMK 264

  Fly   226 YRNSSLSMLIFLP----DQVDGLSELEKKIVGFK-------PKLSKMDVTLRLPKFKIEFFAQLN 279
            |....||||:.||    |.|:.|.||||||...|       ..||:..|.:..|:|.:|....|.
Mouse   265 YAMGKLSMLVLLPSCSEDNVNSLQELEKKINHEKLLAWSSSENLSEKPVAISFPQFNLEDSYDLK 329

  Fly   280 KVLVAMGIQDAF-EKSADFKDLVENSNVHVKKVIHKAFIEVNEEGAEAAAATALLFVRYSMPMPS 343
            .:|..|||:|.| |..||...:.::.|:::.|::||.|:||:|.|.:||||:.::....::|
Mouse   330 SILQDMGIKDVFDETKADLTGISKSPNLYLSKIVHKTFVEVDEMGTQAAAASGVVAAEKALP--- 391

  Fly   344 SQMVFNADHPFAYVIRDRET--IYFQGHFVKP 373
            |.:.|||:|||.:.||...|  :.|.|....|
Mouse   392 SWVEFNANHPFLFFIRHNPTQSLLFCGRVYCP 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	serpin42Dd-like_insects	12..373	CDD:381070	130/419 (31%)
Serpinb12	NP_082247.1	serpinB12_yukopin	1..423	CDD:381037	131/420 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..106		5/42 (12%)