Protein Alignment Spn28F and Serpina12

DIOPT Version :10

• Sequence 1: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_080811.1
• Gene: Serpina12 / 68054
• MGIID: 1915304
• Length: 413
• Species: Mus musculus
• Alignment Length: 348
• Identity: 101/348 - (29%)
• Similarity: 180/348 - (51%)
• Gaps: 14/348 - (4%)

  Fly    17 FADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLKLPD-DKKEVAAKYKDL 80
            |.....|.||..:...|:..||||:..|.||..:||:..|.:|:|......: ...:|.|.:..|
Mouse    55 FGFKLLQRLASNSPQGNIFLSPLSISTAFSMLSLGAQNSTLEEIREGFNFKEMSNWDVHAAFHYL 119

  Fly    81 LSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDPNKASSIVNNWVDNQ 145
            |.||....:...::|.|.:::::|.:....:..:.|:.:.|:....:..|.......:|.::..:
Mouse   120 LHKLNQETEDTKMNLGNALFMDQKLRPQQRFLNLAKNVYDADMVLTNFQDLENTQKDINRYISQK 184

  Fly   146 TRGKIKDLVSSNDMSKMELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVPVEMMSLFQSFR 210
            |..:||::|.|.|...: :|:.|.|||:|:|:|:|:||.||:..|.:...|:|.|.||.....:.
Mouse   185 THSRIKNMVKSIDPGTV-MILTNYIYFRGRWQYEFDPKQTKEEEFFIEKGKTVKVPMMFQRGLYD 248

  Fly   211 AAHDSELGAKIIELPYRNSSLSMLIFLPDQVDGLSELEKKI-----VGFKPKLSKMDVTLRLPKF 270
            .|:||:|...|:|:||| .:::....|||. ..|..||:.:     ..:|..|||..|.:.:||.
Mouse   249 MAYDSQLSCTILEIPYR-GNITATFVLPDN-GKLKLLEQGLQADIFAKWKSLLSKRVVDVWVPKL 311

  Fly   271 KIEFFAQLNKVLVAMGIQDAFEKSADFKDLVENSNVHVKKVIHKAFIEVNEEGAEAAAATALLFV 335
            :|.....:.|||..:||...||::.|...:..:.::.|.:.:|||.::::|:|.|.||.:.
Mouse   312 RISSTYNMKKVLSRLGISKIFEENGDLTRISSHRSLKVGEAVHKAELKMDEKGMEGAAGSG---- 372

  Fly   336 RYSMPMPSSQMVFNADHPFAYVI 358
            ..::||.:.:.: ..|.||..:|
Mouse   373 AQTLPMETPRHM-KLDRPFLMMI 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	serpin42Dd-like_insects	12..373	CDD:381070	101/348 (29%)
Serpina12	NP_080811.1	serpinA12_vaspin	40..411	CDD:381026	101/348 (29%)
		Reactive center loop. /evidence=ECO:0000250|UniProtKB:Q8IW75	364..382		6/21 (29%)