DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn28F and Serpinb1a

DIOPT Version :9

Sequence 1:NP_524957.2 Gene:Spn28F / 49807 FlyBaseID:FBgn0028987 Length:375 Species:Drosophila melanogaster
Sequence 2:NP_079705.2 Gene:Serpinb1a / 66222 MGIID:1913472 Length:379 Species:Mus musculus


Alignment Length:379 Identity:130/379 - (34%)
Similarity:209/379 - (55%) Gaps:20/379 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 TSVSCRFADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLKLPDDKKEVAA 75
            :|.:..||.:.:|.|.:.:...|:..||.|:..||:|..:||:..||.::...... |..:::.:
Mouse     5 SSANTLFALELFQTLNESSPTGNIFFSPFSISSALAMVILGAKGSTAAQLSKTFHF-DSVEDIHS 68

  Fly    76 KYKDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDPNK-ASSIVN 139
            :::.|.:::..|....||.||||:|..|.:..:|.|....:..:.|:...:|.:..:: |...:|
Mouse    69 RFQSLNAEVSKRGASHTLKLANRLYGEKTYNFLPEYLASTQKMYGADLAPVDFLHASEDARKEIN 133

  Fly   140 NWVDNQTRGKIKDLVSSNDMSKM-ELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVPVEMM 203
            .||..||.|||.:|:|...:..| :|:::|||||||.||.||..:.|....||:|.:.:..|:||
Mouse   134 QWVKGQTEGKIPELLSVGVVDSMTKLVLVNAIYFKGMWEEKFMTEDTTDAPFRLSKKDTKTVKMM 198

  Fly   204 SLFQSFRAAHDSELGAKIIELPYRNSSLSMLIFLP----DQVDGLSELEKKIVGFK-------PK 257
            ...:.|...:.|:|..|::|:||:...|||:|.||    |:..||.::||:|...|       ..
Mouse   199 YQKKKFPFGYISDLKCKVLEMPYQGGELSMVILLPKDIEDESTGLKKIEKQITLEKLLEWTKREN 263

  Fly   258 LSKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAFEKS-ADFKDLVENSNVHVKKVIHKAFIEVNE 321
            |..:||.::||:||||....||..|..:|:||.|..| ||...:..:.::.:.|::||:|:||||
Mouse   264 LEFIDVHVKLPRFKIEESYTLNSNLGRLGVQDLFSSSKADLSGMSGSRDLFISKIVHKSFVEVNE 328

  Fly   322 EGAEAAAATALLFVRYSMPMPSSQMVFNADHPFAYVIRDRET--IYFQGHFVKP 373
            ||.||||||..: ..:.|.:|..:  |..||||.:.||...|  :.|.|....|
Mouse   329 EGTEAAAATGGI-ATFCMLLPEEE--FTVDHPFIFFIRHNPTSNVLFLGRVCSP 379

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn28FNP_524957.2 SERPIN 14..370 CDD:238101 128/371 (35%)
Serpinb1aNP_079705.2 serpinB1_LEI 1..379 CDD:381028 129/377 (34%)
CARD-binding motif (CBM). /evidence=ECO:0000250|UniProtKB:P30740 351..379 10/29 (34%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG57242
OrthoDB 1 1.010 - - D556621at33208
OrthoFinder 1 1.000 - - FOG0000050
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100128
Panther 1 1.100 - - O PTHR11461
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X28
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
98.930

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