Protein Alignment Spn28F and SERPINB3

DIOPT Version :10

• Sequence 1: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_008850.1
• Gene: SERPINB3 / 6317
• HGNCID: 10569
• Length: 390
• Species: Homo sapiens
• Alignment Length: 389
• Identity: 128/389 - (32%)
• Similarity: 208/389 - (53%)
• Gaps: 29/389 - (7%)

  Fly    11 TSVSCRFADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLKLP-------- 67
            :..:.:|..|.:|...| :..||:..||:|:..||.|..:||:..|||:::.||...
Human     5 SEANTKFMFDLFQQFRK-SKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTTG 68

  Fly    68 -------DDKKEVAAKYKDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEA 125
                   |....|..:::.||::.........|.:||:::..|.:..:..|...:|..:....|:
Human    69 KAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAIKKFYQTSVES 133

  Fly   126 IDIVD-PNKASSIVNNWVDNQTRGKIKDLVSSNDM-SKMELIVLNAIYFKGQWEYKFNPKLTKKR 188
            :|..: |.::...:|:||::||..|||:|:...:: |...|:::||||||||||.|||.:.||:.
Human   134 VDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQWEKKFNKEDTKEE 198

  Fly   189 NFRVSDQKSVPVEMMSLFQSFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVDGLSELEKKIVG 253
            .|..:......::||..:.||..|...::.||::|:||:...|||::.||:::|||.:||:|:..
Human   199 KFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLTA 263

  Fly   254 FK-------PKLSKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAFEKSADFKDLVENSNVHVKKV 311
            .|       ..:.:..|.|.||:||:|....|...|..||:.|.|...||...:..:..:.:..|
Human   264 EKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFNGDADLSGMTGSRGLVLSGV 328

  Fly   312 IHKAFIEVNEEGAEAAAATALLFVRYSMPMPSSQMVFNADHPFAYVIRDRET--IYFQGHFVKP 373
            :||||:||.|||||||||||:  |.:.....|:...|:.:|||.:.||..:|  |.|.|.|..|
Human   329 LHKAFVEVTEEGAEAAAATAV--VGFGSSPTSTNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	serpin42Dd-like_insects	12..373	CDD:381070	127/386 (33%)
SERPINB3	NP_008850.1	serpinB3_B4_SCCA1_2	1..390	CDD:381030	127/387 (33%)