DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28F and Serpina3i

DIOPT Version :9

Sequence 1:	NP_524957.2	Gene:	Spn28F / 49807	FlyBaseID:	FBgn0028987	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	XP_017170641.1	Gene:	Serpina3i / 628900	MGIID:	2182841	Length:	457	Species:	Mus musculus

Alignment Length:	395	Identity:	118/395 - (29%)
Similarity:	200/395 - (50%)	Gaps:	59/395 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLATSVSCRFADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMR-----NVLKLP 67
            |...|.:..||...|:.|..:|...|::.||.|:..||::..:||::.|.:|:.     |:.:.|
Mouse    70 LTVASSNTDFAFSLYRKLVLKNPDENVVFSPFSIFTALALLSLGAKSNTLKEILEGLKFNLTETP 134

  Fly    68 DDKKEVAAKY-KDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDP 131
            :.......:| .||||:...:.:::|   .:.::|.|..|::..:.:..:..:.|||...|.:.|
Mouse   135 EPDIHQGFRYLLDLLSQPGDQVQIST---GSALFVEKHLQILAEFKEKARALYQAEAFTADFLQP 196

  Fly   132 NKASSIVNNWVDNQTRGKIKDLVSSNDMSKMELIVLNAIYFK--------------GQWEYKFNP 182
            .:|..::|::|.|||:||||:|:|..|.|.: ::::|.||||              |:|:..|:|
Mouse   197 CQAKKLINDYVSNQTQGKIKELISDLDKSTL-MVLVNYIYFKGGRGHCLGVEREELGKWKMPFDP 260

  Fly   183 KLTKKRNFRVSDQKSVPVEMMSLFQ----SFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVDG 243
            :.|....|.:.:::||.|.||.:.:    .||   |.||...::||.|..:: |.|..|||| ..
Mouse   261 RDTFNSKFYLDEKRSVKVPMMKIEELTTPYFR---DDELSCSVVELKYTGNA-SALFILPDQ-GK 320

  Fly   244 LSELEKKI---------VGFKP-KLSKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAFEKSADFK 298
            :.::|..:         ...|| ::|:    |.||||.|.....|..||..:||::.|...||..
Mouse   321 MQQVETSLHPETLRKWKNSLKPSRISE----LHLPKFSISNDYSLEHVLPVLGIREVFSMQADLS 381

  Fly   299 DLVENSNVHVKKVIHKAFIEVNEEGAEAAAATAL-LFVR----YSMPMPSSQMVFNADHPFAYVI 358
            .:....::.|.:|:|||.::|.|.|.||||||.: :.:|    |||.:...:       ||..:|
Mouse   382 AITGTMDLRVSQVVHKAVLDVTETGTEAAAATGVKVNLRCGKIYSMTIYFKR-------PFLIII 439

  Fly   359 RDRET 363
            .|..|
Mouse   440 SDINT 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	116/389 (30%)
Serpina3i	XP_017170641.1	serpinA3_A1AC	62..457	CDD:381019	118/395 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010