Protein Alignment Spn28F and SERPINF2

DIOPT Version :9

• Sequence 1: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: XP_005256758.2
• Gene: SERPINF2 / 5345
• HGNCID: 9075
• Length: 507
• Species: Homo sapiens
• Alignment Length: 394
• Identity: 117/394 - (29%)
• Similarity: 186/394 - (47%)
• Gaps: 81/394 - (20%)

  Fly    17 FADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLK------LPDDKKEVAA 75
            |..|.:.|:|:.:...|||.|||||.:|||...:||:..|.|.::.||.      ||
Human   105 FTADLFSLVAQTSTCPNLILSPLSVALALSHLALGAQNHTLQRLQQVLHAGSGPCLP-------- 161

  Fly    76 KYKDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDPNKAS----- 135
               .|||:|..........||.|:|:.|.|.        :|:.|:.::|.:....|...:
Human   162 ---HLLSRLCQDLGPGAFRLAARMYLQKGFP--------IKEDFLEQSEQLFGAKPVSLTGKQED 215

  Fly   136 --SIVNNWVDNQTRGKIKDLVSSNDMSKMELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSV 198
              :.:|.||...|.|||::.:|......: |::||||:|:|.|..||:|.||::.:|.:.:|.:|
Human   216 DLANINQWVKEATEGKIQEFLSGLPEDTV-LLLLNAIHFQGFWRNKFDPSLTQRDSFHLDEQFTV 279

  Fly   199 PVEMMS----------LFQ-SFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVD--------GL 244
            |||||.          |.| ..:.||          .|::| ::|.::.:|...:        .|
Human   280 PVEMMQARTYPLRWFLLEQPEIQVAH----------FPFKN-NMSFVVLVPTHFEWNVSQVLANL 333

  Fly   245 S--ELEKKIVGFKPKLSKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAFEKSADFKDLVENSNVH 307
            |  .|...:|..:|      ..:||||..::....|...|..:|:|:.|: :.|.:.:.|.|.|
Human   334 SWDTLHPPLVWERP------TKVRLPKLYLKHQMDLVATLSQLGLQELFQ-APDLRGISEQSLV- 390

  Fly   308 VKKVIHKAFIEVNEEGAEAAAATALLFVRYSMPMPSSQMVFNADHPFAYVIRDRET--IYFQGHF 370
            |..|.|::.:|::|.|.||||||::...|.|:   ||   |:.:.||.:.|.:..|  ..|.|..
Human   391 VSGVQHQSTLELSEVGVEAAAATSIAMSRMSL---SS---FSVNRPFLFFIFEDTTGLPLFVGSV 449

  Fly   371 VKPN 374
            ..||
Human   450 RNPN 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	115/388 (30%)
SERPINF2	XP_005256758.2	alpha2AP	98..449	CDD:239008	115/388 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010