Protein Alignment Spn28F and SERPINB13

DIOPT Version :10

• Sequence 1: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_001294852.1
• Gene: SERPINB13 / 5275
• HGNCID: 8944
• Length: 400
• Species: Homo sapiens
• Alignment Length: 399
• Identity: 128/399 - (32%)
• Similarity: 208/399 - (52%)
• Gaps: 41/399 - (10%)

  Fly    12 SVSCRFADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLKLPDDKK--EVA 74
            :||.|...|.::.|.|.| ..|:..||:.:..|:.|..:|.|..||.::..|.....:.|  .:.
Human     6 AVSTRLGFDLFKELKKTN-DGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIK 69

  Fly    75 AKYKDLLS-KLEGRE------------KVAT----------LSLANRIYVNKKFQLVPSYNQMVK 116
            |:.|:::. |.||:|            |..|          |::.||::..|.:..:..|...|:
Human    70 AEEKEVVRIKAEGKEIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVE 134

  Fly   117 DSFMAEAEAIDIVD-PNKASSIVNNWVDNQTRGKIKDLVSSNDM-SKMELIVLNAIYFKGQWEYK 179
            ..:.|..|.:|.|: .:::...:|:||:::|..|||||.....: |..:|:::|.:||||||:.:
Human   135 KYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDRE 199

  Fly   180 FNPKLTKKRNFRVSDQKSVPVEMMSLFQSFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVDGL 244
            |..:.||:..|.::...|..|:||:...||......:|.|||:.:||:|:.|||.:.||:.:|||
Human   200 FKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPNDIDGL 264

  Fly   245 SEL------EKKIVGFKP-KLSKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAF-EKSADFKDLV 301
            .::      ||.:....| .:.:..|.|.||:|::|....|..||.|||:.||| |..||:..:.
Human   265 EKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFSEHKADYSGMS 329

  Fly   302 ENSNVHVKKVIHKAFIEVNEEGAEAAAATALLFVRYSMPMPSSQMVFNADHPFAYVIRDRE--TI 364
            ..|.::.:|.:|.:|:.|.|||.||||||.:.|...|.|...:   .:.:|||.:.||..|  :|
Human   330 SGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPGHEN---VHCNHPFLFFIRHNESNSI 391

  Fly   365 YFQGHFVKP 373
            .|.|.|..|
Human   392 LFFGRFSSP 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	serpin42Dd-like_insects	12..373	CDD:381070	127/397 (32%)
SERPINB13	NP_001294852.1	serpinB13_headpin	1..400	CDD:381038	127/397 (32%)