Protein Alignment Spn28F and SERPINI1

DIOPT Version :9

• Sequence 1: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_001116224.1
• Gene: SERPINI1 / 5274
• HGNCID: 8943
• Length: 410
• Species: Homo sapiens
• Alignment Length: 392
• Identity: 117/392 - (29%)
• Similarity: 201/392 - (51%)
• Gaps: 28/392 - (7%)

  Fly     6 LLLLATSVSCRFADD--------FYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRN 62
            |:|.:.:....|.::        .|..|.......|::.||||:.:|:.|..:||:..|.:|:|:
Human    10 LVLQSMATGATFPEEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRH 74

  Fly    63 VLKLPDDKK-EVAAKYKDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAI 126
            .:.....|. |..:..|:..:.:..:|....:.:||.::|...|.:...:.||:|..|.|....:
Human    75 SMGYDSLKNGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHV 139

  Fly   127 DIVDPNKASSIVNNWVDNQTRGKIKDLVSSNDM-SKMELIVLNAIYFKGQWEYKFNPKLTKKRNF 190
            |.......::.:|.||:|.|...:|||||..|. :...|.::||:||||.|:.:|.|:.|:..:|
Human   140 DFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSF 204

  Fly   191 RVSDQKSVPVEMM----SLFQSFRAAHDSELGA--KIIELPYRNSSLSMLIFLPDQVDGLSELE- 248
            ...|:..|.:.||    ..:....:...:|.|.  :::|:||....:||::.|..|...|:.||
Human   205 TKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEP 269

  Fly   249 ----KKIVGFKPKLSKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAFEKSADFKDLVENSNVHVK 309
                :.:..:...:.|..|.:.||:|.:|....|..||.|:||.:.|.|.|:...|.:|..:.:.
Human   270 LVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLSDNKEIFLS 334

  Fly   310 KVIHKAFIEVNEEGAEAAAATALLFV-RYSMPMPSSQMVFNADHPFAYVIRDRE--TIYFQGHFV 371
            |.|||:|:||||||:||||.:.::.: |.::..|  |::  .||||.::||:|.  ||.|.|..:
Human   335 KAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYP--QVI--VDHPFFFLIRNRRTGTILFMGRVM 395

  Fly   372 KP 373
            .|
Human   396 HP 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	114/379 (30%)
SERPINI1	NP_001116224.1	neuroserpin	23..410	CDD:239003	114/379 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3483
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.960