Protein Alignment Spn28F and SERPINB6

DIOPT Version :10

• Sequence 1: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: XP_011512974.1
• Gene: SERPINB6 / 5269
• HGNCID: 8950
• Length: 454
• Species: Homo sapiens
• Alignment Length: 375
• Identity: 129/375 - (34%)
• Similarity: 211/375 - (56%)
• Gaps: 27/375 - (7%)

  Fly    17 FADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLKLPDDKK----EVAAKY 77
            ||.:..:.|.|:| :.|:..||:|:..||:|.||||:..||.:|..:|..  :|.    ::...:
Human    89 FALNLLKTLGKDN-SKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF--NKSGGGGDIHQGF 150

  Fly    78 KDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVDP-NKASSIVNNW 141
            :.||:::........|.:|||::..|....:.|:....:..:.||.|.:|.:.. .|:...:|.|
Human   151 QSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTW 215

  Fly   142 VDNQTRGKIKDLVSSNDMSKM-ELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVPVEMMSL 205
            |..:|.|||.:|:|...:..: .|:::||:||:|.|:.:|:.:.|::|.|:||..:..||:||..
Human   216 VAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFK 280

  Fly   206 FQSFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVDGLSELEKKIVGFK----PKLSKMD---V 263
            ..:|:..:..|:..:|:.|||....|:|:|.|||:...|..:||::...|    .:|..||   |
Human   281 QSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEKELTYEKFVEWTRLDMMDEEEV 345

  Fly   264 TLRLPKFKIEFFAQLNKVLVAMGIQDAFE-KSADFKDLVENSNVHVKKVIHKAFIEVNEEGAEAA 327
            .:.||:||:|....:..||..:|:.|||| ..|||..: ..:::.:.||:||:|:||||||.|||
Human   346 EVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGM-SQTDLSLSKVVHKSFVEVNEEGTEAA 409

  Fly   328 AATALLFVRYSMPMPSSQMV--FNADHPFAYVIRDRET--IYFQGHFVKP 373
            ||||.:     |.|..::.|  |.|||||.:.|:..:|  |.|.|.|..|
Human   410 AATAAI-----MMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSSP 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	serpin42Dd-like_insects	12..373	CDD:381070	128/373 (34%)
SERPINB6	XP_011512974.1	serpinB6_CAP	79..454	CDD:381031	128/373 (34%)