Protein Alignment Spn28F and SERPINA4

DIOPT Version :9

• Sequence 1: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Sequence 2: NP_001275961.1
• Gene: SERPINA4 / 5267
• HGNCID: 8948
• Length: 464
• Species: Homo sapiens
• Alignment Length: 392
• Identity: 114/392 - (29%)
• Similarity: 181/392 - (46%)
• Gaps: 56/392 - (14%)

  Fly    17 FADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMR-----NVLKLPDDKKEVAAK 76
            ||..||.|:|.|....|:..||||:..|.:|..:||.:.:..::.     |:.:|  .:.:|...
Human    95 FAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTEL--SESDVHRG 157

  Fly    77 YKDLLSKL----EGRE-KV-ATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEA----IDIVDP 131
            ::.||..|    .|.| :| :.|.|::.:....||         :.|: ||..||    .:..|.
Human   158 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKF---------LNDT-MAVYEAKLFHTNFYDT 212

  Fly   132 NKASSIVNNWVDNQTRGKIKDLVSSNDMSKMELIVL-NAIYFKGQWEYKFNPKLTKKRNFRVSDQ 195
            .....::|:.|..:|||||.||||  ::.|..|:|| |.||||..||..|....|..::|.|.:.
Human   213 VGTIQLINDHVKKETRGKIVDLVS--ELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDEN 275

  Fly   196 KSVPVEMMSLFQSFR-AAHDSELGAKIIELPYRNSSLSMLIFLPDQVDGLSELEKKIV------- 252
            .:|.|.||...|... ..||..|...::.:.|:..: ::...||:| ..:.|:|:.:.
Human   276 TTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDA-TVFFILPNQ-GKMREIEEVLTPEMLMRW 338

  Fly   253 -------GFKPKLSKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAFEKSADFKDLVENSNVHVKK 310
                   .|..||.     |.||||.|.....|:::|..:|..|.|.|.||...:.:...:...|
Human   339 NNLLRKRNFYKKLE-----LHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASK 398

  Fly   311 VIHKAFIEVNEEGAEAAAATALLFVRYSMPMPSSQMVFNADHPFAYVI--RDRETIYFQGHFVKP 373
            ..|||.::|:|.|.||||||:.....:|  ..:::.:...:.||..||  ...:::.|.|..|.|
Human   399 SFHKATLDVDEAGTEAAAATSFAIKFFS--AQTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 461

  Fly   374 NE 375
            .:
Human   462 TK 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	112/385 (29%)
SERPINA4	NP_001275961.1	alpha-1-antitrypsin_like	91..458	CDD:239011	112/385 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.020