DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28F and serpinc1

DIOPT Version :9

Sequence 1:	NP_524957.2	Gene:	Spn28F / 49807	FlyBaseID:	FBgn0028987	Length:	375	Species:	Drosophila melanogaster
Sequence 2:	NP_001008153.1	Gene:	serpinc1 / 493515	XenbaseID:	XB-GENE-975782	Length:	456	Species:	Xenopus tropicalis

Alignment Length:	382	Identity:	109/382 - (28%)
Similarity:	196/382 - (51%)	Gaps:	22/382 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 TSVSCRFADDFYQLLA--KENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLKLPDDKKEV 73
            :..:.:||..||:.||  |:| ..|:..||||:..|.:||.:||...|.:|:..|.......:..
Frog    75 SQANAKFAIAFYKNLADSKQN-TENIFMSPLSISQAFTMAKLGACNNTLKELMEVFYFDTISERA 138

  Fly    74 AAKYKDLLSKLEGR-----EKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVD-PN 132
            :.:.....:||..|     .|.:.|...||::..|......:|..:.:..:.|:...::..: |.
Frog   139 SDQIHYFFAKLNCRLFRKANKSSELVSVNRLFGEKSLTFNETYQDISELVYGAKLLPLNFKEKPE 203

  Fly   133 KASSIVNNWVDNQTRGKIKDLVSSNDMS-KMELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQK 196
            .:..|:||||.::|..:|.|::....:: ...|:::|||||||.|:.|||.:.||...|...:..
Frog   204 LSREIINNWVSDKTEKRITDVIPVGVITPDTVLVLINAIYFKGLWKSKFNSENTKMEQFYPDESN 268

  Fly   197 SVPVEMMSLFQSFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVDGLSELE-----KKIVGFKP 256
            ......|.....||.:...:.|.:::||||:...::|::.||.....|.::|     :|:..:..
Frog   269 HCLAATMYQEGIFRYSSFKDDGVQVLELPYKGDDITMVLVLPSPETPLMKVEQNLTLEKLGNWLQ 333

  Fly   257 KLSKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAFE-KSADFKDLVE--NSNVHVKKVIHKAFIE 318
            |..::.:::.||:|::|....:.:.|..||:.|.|: .||....:|.  .::::|....||||:|
Frog   334 KSRELQLSVYLPRFRVEDSFSVKEKLQQMGLVDLFDPNSAKLPGIVAGGRTDLYVSDAFHKAFLE 398

  Fly   319 VNEEGAEAAAATALLFVRYSMPMPSSQMVFNADHPFAYVIRD--RETIYFQGHFVKP 373
            |||||:||||:||::....|:.:  :::.|.|:.||...||:  ..::.|.|....|
Frog   399 VNEEGSEAAASTAVILTGRSLNL--NRITFRANRPFLVFIREVAINSVLFMGRVANP 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	108/374 (29%)
serpinc1	NP_001008153.1	serpinC1_AT3	61..455	CDD:381002	109/382 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.110